Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

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Fluorescent probes are an indispensable tool in the realm of bioimaging technologies, providing valuable insights into the assessment of biomaterial integrity and structural properties. However, incorporating fluorophores into scaffolds made from melt elec ...

Fluorescence confocal laser-scanning microscopy (LSM) is one of the most popular tools for life science research. This popularity is expected to grow thanks to single-photon array detectors tailored for LSM. These detectors offer unique single-photon spati ...

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The pharmacometric analysis of the double-blind, randomized, phase II study (NCT02975349) investigating the safety and efficacy of evobrutinib, explored exposure-response relationships and suitable dosing regimens of evobrutinib for relapsing multiple scle ...

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ABCG2 is a multidrug transporter that affects drug pharmacokinetics and contributes to multidrug resistance of cancer cells. In previously reported structures, the reaction cycle was halted by the absence of substrates or ATP, mutation of catalytic residue ...

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Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

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[n]Cycloparaphenylenes as Compatible Fluorophores for Melt Electrowriting

Compact and effective photon-resolved image scanning microscope

Development of tools and methods for protein identification: From single molecules to in vivo applications

Wideband integrated bioaerosol sensor (WIBS) excited, fluorescent, and hyper-fluorescent particle number concentrations and normalized size distributions (dN/dlogDp) measured in the Swiss container during MOSAiC 2019/2020

A general strategy to develop fluorogenic polymethine dyes for bioimaging

Generating macrocyclic inhibitors of protein-protein interactions

Establishing a Ternary System for Optical Monitoring of DNA-Protein Interactions with Single-Walled Carbon Nanotubes

Azacyanine dyes and use thereof

Multivalent Peptide Ligands To Probe the Chromocenter Microenvironment in Living Cells

Azacyanine dyes and use thereof

Determination of a clinically effective evobrutinib dose: Exposure-response analyses of a phase II relapsing multiple sclerosis study

Image-Based Marker-Free Screening of GABA(A) Agonists, Antagonists, and Modulators

Generation of a Gal4-dependent gene recombination and illuminating mouse

Innovative Tools and in vivo Methods for Tuberculosis Drug Discovery and Development

Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism

Detection of mRNA by Whole Mount in situ Hybridization and DNA Extraction for Genotyping of Zebrafish Embryos

Single-photon avalanche diode imaging sensor for subsurface fluorescence LiDAR

Single-molecule localization microscopy

Real-Time Imaging and Quantification of Peptide Uptake in Vitro and in Vivo

Directed evolution of DNA-wrapped single-walled carbon nanotube complexes for optical sensing