Publications related to Approximation of Event Probabilities in Noisy Cellular Processes

Related publications (32)

Mean value theorems for collections of lattices with a prescribed group of symmetries

Euclidean lattices are mathematical objects of increasing interest in the fields of cryptography and error-correcting codes. This doctoral thesis is a study on high-dimensional lattices with the motivation to understand how efficient they are in terms of b ...

EPFL2024

Technosignatures Longevity and Lindy's Law

Claudio Grimaldi

The probability of detecting technosignatures (i.e., evidence of technological activity beyond Earth) increases with their longevity, or the time interval over which they manifest. Therefore, the assumed distribution of longevities has some bearing on the ...

Iop Publishing Ltd2024

Experimental characterization and stochastic models for time-dependent rupture of thin-ply composite laminates

Kanthasamy Ubamanyu

Thin-laminate composites with thicknesses below 200 mu m hold significant promise for future, larger, and lighter deployable structures. This paper presents a study of the time-dependent failure behavior of thin carbon-fiber laminates under bending, focusi ...

2024

A multigrid method for PDE-constrained optimization with uncertain inputs

Fabio Nobile, Tommaso Vanzan

In this manuscript, we present a collective multigrid algorithm to solve efficiently the large saddle-point systems of equations that typically arise in PDE-constrained optimization under uncertainty, and develop a novel convergence analysis of collective ...

Springer Science and Business Media LLC2024

Modeling, analysis, and design of complex biological networks

Mohammadomid Oftadeh

Automating experimental procedures has resulted in an unprecedented increase in the volume of generated data, which, in turn, has caused an accumulation of unprocessed data. As a result, the need to develop tools to analyze data systematically has been ris ...

EPFL2023

Personalized Privacy-Preserving Distributed Learning on Heterogeneous Data

Michael Christoph Gastpar, Aditya Pradeep

One major challenge in distributed learning is to efficiently learn for each client when the data across clients is heterogeneous or non iid (not independent or identically distributed). This provides a significant challenge as the data of the other client ...

2023

Preconditioners for robust optimal control problems under uncertainty

Fabio Nobile, Tommaso Vanzan

The discretization of robust quadratic optimal control problems under uncertainty using the finite element method and the stochastic collocation method leads to large saddle-point systems, which are fully coupled across the random realizations. Despite its ...

2023

Influence of advanced footwear technology on sub-2 hour marathon and other top running performances

Raphaël Gérard Théodore Michel Marie de Deloÿe et Fourcade de Fondeville

In 2019, Eliud Kipchoge ran a sub-two hour marathon wearing Nike's Alphafly shoes. Despite being the fastest marathon time ever recorded, it wasn't officially recognized as race conditions were tightly controlled to maximize his success. Besides, Kipchoge' ...

WALTER DE GRUYTER GMBH2022

A Functional Perspective on Information Measures

Amedeo Roberto Esposito

Since the birth of Information Theory, researchers have defined and exploited various information measures, as well as endowed them with operational meanings. Some were born as a "solution to a problem", like Shannon's Entropy and Mutual Information. Other ...

EPFL2022

Toward Mobile Distributed Ledgers

Boi Faltings, Sujit Prakash Gujar

Advances in mobile computing have paved the way for new types of distributed applications that can be executed solely by mobile devices on Device-to-Device (D2D) ecosystems (e.g., crowdsensing). Sophisticated applications, like cryptocurrencies, need distr ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Waterborne virus transport and the associated risks in a large lake

Tamar Kohn, Timothy R. Julian, Xavier Fernandez Cassi, Chaojie Li

Waterborne enteric viruses in lakes, especially at recreational water sites, may have a negative impact on human health. However, their fate and transport in lakes are poorly understood. In this study, we propose a coupled water quality and quantitative mi ...

2022

Nuclear Excitation by Free Muon Capture

Fabrizio Carbone, Ivan Madan, Simone Gargiulo

Efficient excitation of nuclei via exchange of a real or virtual photon has a fundamental importance for nuclear science and technology development. Here, we present a mechanism of nuclear excitation based on the capture of a free muon into the atomic orbi ...

AMER PHYSICAL SOC2022

Effect of wastewater treatment and environmental exposure on an enterovirus population

Odile Marie Clotilde Hervás de Nalda-Larivé

The presence of viruses in recreational water can present a risk for human health and wastewater effluent is a source of virus in the environment. Their persistence in the environment influences their probability to find a new host. Studies have shown that ...

EPFL2022

ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Giovanni D'Angelo, Francisco De Magalhães Sarmento Ribeiro De Mesquita, Oksana Andrei Sergeeva, Laura Capolupo, Audrey Geneviève Chuat, Muhammad Umair Anwar, Triana Amen

To promote infections, pathogens exploit host cell machineries such as structural elements of the plasma membrane. Studying these interactions and identifying molecular players are ideal for gaining insights into the fundamental biology of the host cell. H ...

Cell Press - Elsevier2022

Generalization Error Bounds Via Rényi-, f-Divergences and Maximal Leakage

Michael Christoph Gastpar, Amedeo Roberto Esposito, Ibrahim Issa

In this work, the probability of an event under some joint distribution is bounded by measuring it with the product of the marginals instead (which is typically easier to analyze) together with a measure of the dependence between the two random variables. ...

2021

Predicting involuntary hospitalization in psychiatry: A machine learning investigation

Mehdi Gholam

Background Coercion in psychiatry is a controversial issue. Identifying its predictors and their interaction using traditional statistical methods is difficult, given the large number of variables involved. The purpose of this study was to use machine-lear ...

CAMBRIDGE UNIV PRESS2021

Semi-Discrete Optimal Transport: Hardness, Regularization and Numerical Solution

Daniel Kuhn, Soroosh Shafieezadeh Abadeh, Bahar Taskesen

Semi-discrete optimal transport problems, which evaluate the Wasserstein distance between a discrete and a generic (possibly non-discrete) probability measure, are believed to be computationally hard. Even though such problems are ubiquitous in statistics, ...

2023

KRAB zinc finger protein-mediated control of transposon-embedded regulatory sequences from human germline to early embryos

Alexandra Iouranova

Transposable elements (TEs), also called jumping genes, are genetic elements capable of changing their position within the genome of their host. They make up large fractions of genomes, including 45% of human DNA content, according to current estimates. S ...

EPFL2021

A Pareto Dominance Principle for Data-Driven Optimization

Daniel Kuhn, Tobias Sutter

We propose a statistically optimal approach to construct data-driven decisions for stochastic optimization problems. Fundamentally, a data-driven decision is simply a function that maps the available training data to a feasible action. It can always be exp ...

2024

COVID-19: data-driven dynamic asset allocation in times of pandemic

Anna Timonina-Farkas

The COVID-19 pandemic has demonstrated the importance and value of multi-period asset allocation strategies responding to rapid changes in market behavior. In this article, we formulate and solve a multi-stage stochastic optimization problem, choosing the ...

AMER INST MATHEMATICAL SCIENCES-AIMS2021