Publication

Divergent Asymmetric Synthesis of Polycyclic Compounds via Vinyl Triazenes

Rosario Scopelliti, Kay Severin, Nicolai Cramer, Gregor Kiefer, Abdusalom Suleymanov, David Kossler, Florian Gérald Abela
2017
Journal Articles

Abstract

Vinyl triazenes were obtained by enantioselective [2+2] cycloaddition reactions of bicyclic alkenes with 1-alkynyl triazenes in the presence of a RuII catalyst with a chiral cyclopentadienyl ligand. These triazenes serve as unique vinyl cation surrogates. Under acidic conditions, the triazene functionality can be replaced with a variety of groups, including halides, alkoxides, sulfoxides, amides, arenes, and heteroarenes, thus providing efficient access to a pool of chiral polycyclic compounds.

Official source

https://infoscience.epfl.ch/entities/publication/957118aa-699d-441d-b920-4c2cd4a45a19

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Divergent Asymmetric Synthesis of Polycyclic Compounds via Vinyl Triazenes

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