Biologically effective dose correlates with linear tumor volume changes after upfront single-fraction stereotactic radiosurgery for vestibular schwannomas

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Multimodal fusion of liquid biopsy and CT enhances differential diagnosis of early-stage lung adenocarcinoma

Li Zhang, Jiancheng Yang

This research explores the potential of multimodal fusion for the differential diagnosis of early-stage lung adenocarcinoma (LUAD) (tumor sizes < 2 cm). It combines liquid biopsy biomarkers, specifically extracellular vesicle long RNA (evlRNA) and the comp ...

Nature Portfolio2024

Gamma Knife radiosurgery as salvage therapy for gangliogliomas after initial microsurgical resection

Constantin Tuleasca

Introduction: Gangliogliomas (GG) are considered WHO grade I rare tumors. While they commonly manifest as temporal lobe epilepsy, they can be located anywhere in the brain. Primary treatment is complete microsurgical resection. Remnant or recurrent GG can ...

2021

Gain of HIF1 Activity and Loss of miRNA let-7d Promote Breast Cancer Metastasis to the Brain via the PDGF/PDGFR Axis

Amaia Martinez Usatorre

Early detection and adjuvant therapies have significantly improved survival of patients with breast cancer over the past three decades. In contrast, management of metastatic disease remains unresolved. Brain metastasis is a late complication frequently obs ...

AMER ASSOC CANCER RESEARCH2021

Mapping cell lineage growth in human tumors using somatic mitochondrial mutations

Stephan Morgenthaler, Paul Refinetti

Spandidos Publ Ltd2014