Gastruloids generated without exogenous Wnt activation develop anterior neural tissues

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Single-cell and single-nucleus genomic approaches can provide unbiased and multimodal insights. Here, we discuss what constitutes a molecular cell atlas and how to leverage single-cell omics data to generate hypotheses and gain insights into cell transitio ...

Here, we show that, in the developing spinal cord, after the early Wnt-mediated Tcf transcription activation that confers dorsal identity to neural stem cells, neurogenesis redirects beta-catenin from the adherens junctions to the nucleus to stimulate Tcfo ...

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Gastruloids generated without exogenous Wnt activation develop anterior neural tissues

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Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system

Neurogenesis redirects β-catenin from adherens junctions to the nucleus to promote axonal growth

Stroma-Driven Notch2 Signaling Controls Naive B Cell Fate By Regulating Microenvironmental Positioning within the Spleen

Bioengineered embryoids mimic post-implantation development in vitro

Membrane expression of the estrogen receptor ER alpha is required for intercellular communications in the mammary epithelium

Homeostatic mini-intestines through scaffold-guided organoid morphogenesis

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes

ASAP: a web-based platform for the analysis and interactive visualization of single-cell RNA-seq data

Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture