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Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools

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Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools

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C2CAplus: A One-Pot Isothermal Circle-to-Circle DNA Amplification System

cgNA+: A sequence-dependent coarse-grain model of double-stranded nucleic acids

Comparative Evaluation of Lipofectamine and Dendrimer for Transfection of Short RNA Into Human T47D and MCF-10A Cell Lines

Landscapes of DNA Mechanics and Genomes

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase(+) cells and telomeric recombination in ALT(+) cells

Secondary structure of the human mitochondrial genome affects formation of deletions

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

Time-Resolved Scanning Ion Conductance Microscopy and Single-Molecule Spectroscopy

Recombinant Full-Length TDP-43 Oligomers Retain Their Ability to Bind RNAs, Are Not Toxic, and Do Not Seed TDP-43 Aggregation in Vitro

Construction of sequencing libraries from a ribonucleic acid (rna) using tailing and ligation of cdna (tlc)

Dynamics of the most common pathogenic mtDNA variant m.3243A > G demonstrate frequency-dependency in blood and positive selection in the germline

Exploring the mechanisms governing nuclear cGAS localization and activity

Identification and characterization of proteins that protect human telomeres from fragility