Selective Chemical Crosslinking Reveals a Cep57-Cep63-Cep152 Centrosomal Complex

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Centromeres are epigenetically defined via the presence of the histone H3 variant CENP-A. Contacting CENP-A nucleosomes, the constitutive centromere associated network (CCAN) and the kinetochore assemble, connecting the centromere to spindle microtubules d ...

Centrioles are microtubule-based structures crucial for forming flagella, cilia and centrosomes. Through these roles, centrioles are critical notably for proper cell motility, signalling and division. Recent years have advanced significantly our understand ...

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Centrioles are eukaryotic organelles that template the formation of cilia and flagella, as well as organize the microtubule network and the mitotic spindle in animal cells. Centrioles have proximal-distal polarity and a 9 fold radial symmetry imparted by a ...

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Centrioles are evolutionarily conserved multi-protein organelles essential for forming cilia and centrosomes. Centriole biogenesis begins with self-assembly of SAS-6 proteins into 9-fold symmetrical ring polymers, which then stack into a cartwheel that sca ...

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The ninefold radial arrangement of microtubule triplets (MTTs) is the hallmark of the centriole, a conserved organelle crucial for the formation of centrosomes and cilia. Although strong cohesion between MTTs is critical to resist forces applied by ciliary ...

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The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial symmetry. Centrioles play fundamental roles across eukaryotes, notably in cell signaling, motility and division. In this Cell Science at a Glance article and accom ...

Proper spindle positioning is crucial for spatial cell division control. Spindle positioning in human cells relies on a ternary complex comprising G alpha i1-3, LGN and NuMA, which anchors dynein at the cell cortex, thus enabling pulling forces to be exert ...

Selective Chemical Crosslinking Reveals a Cep57-Cep63-Cep152 Centrosomal Complex

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Centromere structure and function: lessons from Drosophila

CENP-A and CENP-B collaborate to create an open centromeric chromatin state

Towards understanding centriole elimination

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

An out-of-equilibrium definition of protein turnover

Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel

Intrinsically High Capacity of Animal Cells From a Symbiotic Cnidarian to Deal With Pro-Oxidative Conditions

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly

Centriole foci persist in starfish oocytes despite Polo-like kinase 1 inactivation or loss of microtubule nucleation activity

A helical inner scaffold provides a structural basis for centriole cohesion

Architecture of the centriole cartwheel‐containing region revealed by cryo‐electron tomography

Fluorogenic probes for live-cell imaging

Roles of Epigenetic Dysregulation in Cancer Progression and Metastasis

Unequal cleavage of the C. elegans zygote ensures robust embryogenesis

A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

A biphasic growth model for cell pole elongation in mycobacteria

Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms

Centriole assembly at a glance

Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells