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Significance: Diffuse correlation spectroscopy (DCS) allows label-free, non-invasive investigation of microvascular dynamics deep within tissue, such as cerebral blood flow (CBF). However, the signal-to-noise ratio (SNR) in DCS limits its effective cerebral sensitivity in adults, in which the depth to the brain, through the scalp and skull, is substantially larger than in infants.
Frank Nüesch, Wei-Hsu Hu, Elodie Didier
Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Takuya Morishita, Elena Beanato, Andrea Crema, Giorgia Giulia Evangelista, Claudia Bigoni, Sarah Bernardina Zandvliet, Julie Loréline Valériane Hervé, Meltem Oflar, Christina Henneken