Publication

Sulfated and sulfonated dendritic polyglycerols and use thereof as broad-spectrum virucidal agents

Francesco Stellacci, Matteo Gasbarri
2022
Patents

Abstract

The invention relates to dendritic polyglycerol (dPG) compounds with alkyl-sulfonate/ sulfate functional groups that irreversibly inhibit viral infection (virucidal effect) through multivalent interaction in nanomolar concentration range. While the compounds of the invention show virus inhibition in the nanomolar range they show no in-vitro toxicity in the same range of concentration.

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