Publication

Towards an Evolutionary Theory of Stress Responses

Related publications (29)

Acute stress alters individual risk taking in a time-dependent manner and leads to anti-social risk

Maria del Carmen Sandi Perez, Samuel Bendahan, Fiona Hollis, John Christian Thoresen, Lorenz Goette, Leyla Loued-Khenissi

Decision-making processes can be modulated by stress, and the time elapsed from stress induction seems to be a crucial factor in determining the direction of the effects. Although current approaches consider the ﬁrst post-stress hour a uniform period, the ...

2017

NEMo: An Evolutionary Model With Modularity for PPI Networks

Bernard Moret, Xiuwei Zhang, Min Ye, Qijia Jiang, Gabriela Clara Racz

Modeling the evolution of biological networks is a major challenge. Biological networks are usually represented as graphs; evolutionary events not only include addition and removal of vertices and edges but also duplication of vertices and their associated ...

IEEE Press2017

Form - function relationships in dragonfly mandibles under an evolutionary perspective

Alessandra Patera

Functional requirements may constrain phenotypic diversification or foster it. For insect mouthparts, the quantification of the relationship between shape and function in an evolutionary framework remained largely unexplored. Here, the question of a functi ...

Royal Soc2017

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

João Miguel das Neves Duarte, Alberto Corcoba

Adverse environmental and social conditions early in life have a strong impact on health. They are major risk factors for mental diseases in adulthood and, in some cases, their effects can be transmitted across generations. The consequences of detrimental ...

Sage Publications Inc2017

Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

Jacques Fellay

HIV-1 set-point viral load-the approximately stable value of viraemia in the first years of chronic infection-is a strong predictor of clinical outcome and is highly variable across infected individuals. To better understand HIV-1 pathogenesis and the evol ...

Public Library Science2017

Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory

Luciano Andres Abriata

The understanding of protein evolution depends on the ability to relate the impact of mutations on molecular traits to organismal fitness. Biological activity and robustness have been regarded as important features in shaping protein evolutionary landscape ...

Oxford Univ Press2016

An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

Hyunjin Shim, Jeffrey David Jensen, Claudia Bank, Matthieu Foll, Sebastian Matuszewski

The rapid evolution of drug resistance remains a critical public health concern. The treatment of influenza A virus (IAV) has proven particularly challenging, due to the ability of the virus to develop resistance against current antivirals and vaccines. He ...

Wiley-Blackwell2016

An Approximate Markov Model for the Wright-Fisher Diffusion and Its Application to Time Series Data

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The joint and accurate inference of selection and demography from genetic data is considered a particularly challenging question in population genetics, since both process may lead to very similar patterns of genetic diversity. However, additional informat ...

Genetics Society America2016

Implication of individual differences in glucocorticoid responsiveness to stress in the development of psychopathology-like behaviour and underlying neurobiology

Sophie Elizabeth Walker

The period around puberty is a critical window in development. It is a time of neuroendocrine and neuroanatomical lability, rendering individuals highly sensitive to stress. Indeed, early adversity increases risk for psychopathology. The mechanisms via whi ...

EPFL2016