Publication

Clinical Validation of a Blood Filtration Element for Plasma Separation at the Point of Care

Nico de Rooij, Alexandra Anne Labiba Kämpfer-Homsy
2011
Conference Papers

Abstract

In this contribution we present our work on filtration of plasma from whole blood in a polymer-based microfluidic system. The absorption of pathogens was found to be low; therefore our system is valid for clinical trials. The blood filtration element is capable of extracting 8–15μL volume of plasma from 100μL of whole blood in 7 minutes.

Official source

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Nico de Rooij, Alexandra Anne Labiba Kämpfer-Homsy
2011
Conference Papers

Abstract

Official source

Related concepts (27)

Blood plasma

Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but which contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. It is the intravascular part of extracellular fluid (all body fluid outside cells). It is mostly water (up to 95% by volume), and contains important dissolved proteins (6–8%; e.g., serum albumins, globulins, and fibrinogen), glucose, clotting factors, electrolytes (Na+, Ca2+, Mg2+, , Cl−, etc.

Blood

Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the circulatory system is also known as peripheral blood, and the blood cells it carries, peripheral blood cells. Blood is composed of blood cells suspended in blood plasma.

Blood type

A blood type (also known as a blood group) is a classification of blood, based on the presence and absence of antibodies and inherited antigenic substances on the surface of red blood cells (RBCs). These antigens may be proteins, carbohydrates, glycoproteins, or glycolipids, depending on the blood group system. Some of these antigens are also present on the surface of other types of cells of various tissues. Several of these red blood cell surface antigens can stem from one allele (or an alternative version of a gene) and collectively form a blood group system.

Related publications (3)

Clinical Validation of a Blood Filtration Element for Plasma Separation at the Point of Care

Chat with Graph Search

Fabrication of microfluidic channels using Si-Si bonding

Why the move to microfluidics for protein analysis?

Photo-polymer microchannel technologies and applications