Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice

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ObjectiveA Delta-Notch signaling component, Notch1, is involved in the normal development and multiple disorders of the kidney. Although the increase in Notch1 signaling is crucial to these pathogeneses, the basal signaling level in 'healthy' mature kidney ...

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Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice

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