Publication

Hydrogen bonds lengths in nucleic acids estimated from longitudinal nitrogen-15 relaxation

Geoffrey Bodenhausen
2003
Journal Articles

Abstract

A new NMR method has been designed for the measurement of the longitudinal relaxation rates of both donor and acceptor nitrogen-15 nuclei in Watson-Crick base pairs in 15N-enriched nucleic acids. The expt. was applied to a 22-nucleotide RNA hairpin. The lengths of four hydrogen bonds could be estd. from the longitudinal relaxation rates. [on SciFinder (R)]

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Geoffrey Bodenhausen
2003
Journal Articles

Abstract

Official source

Related concepts (32)

Hydrogen bond

In chemistry, a hydrogen bond (or H-bond) is a primarily electrostatic force of attraction between a hydrogen (H) atom which is covalently bound to a more electronegative "donor" atom or group (Dn), and another electronegative atom bearing a lone pair of electrons—the hydrogen bond acceptor (Ac). Such an interacting system is generally denoted , where the solid line denotes a polar covalent bond, and the dotted or dashed line indicates the hydrogen bond.

Nucleic acid analogue

Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research. Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pentose sugar, either ribose or deoxyribose, and one of four nucleobases. An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties.

Carbon–hydrogen bond

In chemistry, the carbon-hydrogen bond ( bond) is a chemical bond between carbon and hydrogen atoms that can be found in many organic compounds. This bond is a covalent, single bond, meaning that carbon shares its outer valence electrons with up to four hydrogens. This completes both of their outer shells, making them stable. Carbon–hydrogen bonds have a bond length of about 1.09 Å (1.09 × 10−10 m) and a bond energy of about 413 kJ/mol (see table below). Using Pauling's scale—C (2.55) and H (2.

Related publications (11)

Hydrogen bonds lengths in nucleic acids estimated from longitudinal nitrogen-15 relaxation

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Control of Cross Relaxation of Multiple-Quantum Coherences Induced by Fast Chemical Exchange under Heteronuclear Double-Resonance Irradiation

Ultrafast-based projection-reconstruction three-dimensional nuclear magnetic resonance spectroscopy

SLOW DIFFUSION AND FLOW OF MOLECULES MEASURED BY PULSED FIELD GRADIENT NMR USING LONGITUDINAL MAGNETISATION OF NON-PROTON ISOTOPES