Publication

DNA-PAINT adaptors make for efficient multiplexing

Suliana Manley, Matthew Domenic Lycas
2024

Abstract

Multiplexed super -resolution imaging offers a route to spatial proteomics; however, time -efficient mapping of many protein species has been challenging. Two recent works in Cell highlight SUM -PAINT and FLASHPAINT, methods that leverage adaptor DNA strand design to combine advances in multiplexing with increases in speed of label exchange. These advances permit unbiased omics-style analyses to advance biological insights from super -resolution images.

Official source

https://infoscience.epfl.ch/entities/publication/7a1fab03-96c9-466c-a89b-ff022067e2ba

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