Exploring the genome and ecology of Hydrurus foetidus - the dominant alga in glacier-fed streams

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This study investigates the multi‐decadal evolution of a glacier forefield under permafrost conditions in the Combins Massif (western Swiss Alps). A multi‐method approach based on historical and recent datasets is used to analyze its landform components. To better understand the complex dynamics of landforms and their interactions in environments shaped by glacial and periglacial processes, this study seeks to foster the use and application of a multi‐method approach to capture the multi‐decadal evolution o

Born in 1965 in Xiaoshan (Hangzhou, China), Jieping Zhu moved to France after completing his master's degree to pursue doctoral studies at Université Paris-XI, carried out at the Institut de Chimie des Substances Naturelles (ICSN) under the supervision of Profs. H.-P. Husson and J.-C. Quirion. After postdoctoral research with Sir D. H. R. Barton, he was appointed CNRS Researcher at the ICSN in 1992. From the outset of his career, Jieping Zhu's research has been guided by a clear philosophy: convergent synth

Urban forests are not merely green amenities; they support critical ecosystem functioning and services vital for healthy, resilient cities. Recognising urban forests as core infrastructure is essential to reversing the loss of mature trees, preserving biodiversity, and maintaining liveability amid increasing climate and environmental pressures. Although the benefits of urban forests for climate resilience, biodiversity, and public health are broadly acknowledged, policies to protect and enhance these vital

Published research on climate change in cities is highly uneven, but cities are not equally isolated. We map the geography of urban climate evidence by combining a city-by-domain evidence matrix with domain-specific similarity spaces, allowing us to distinguish direct evidence from the evidence cities can access through comparable analogues. Across vulnerability, adaptation, mitigation, and governance, case study evidence is sparse and concentrated in a limited set of region × type cells, with adaptation co

Mountain glaciers are vanishing worldwide because of climate change, triggering cascading downstream effects. Today, glaciers are recognized as stores of dissolved organic matter (DOM), which once released, can support the microbial metabolism and food webs in glacier-fed streams. This glacier-derived DOM is often reported to be ancient and highly bioavailable. However, our understanding of how such DOM may change in the future, as mountain glaciers continue to melt, remains limited.We aimed to determine wh

In glacierized high mountain catchments, streamflow generation is strongly influenced by snow and glacier melt, processes especially sensitive to rising temperatures and ongoing climate change. These vulnerabilities make mountain headwater catchments a research priority; However, limited observational data and complex glacier-snow interactions often challenge conventional hydrological modeling in high-mountainous areas. Although several models have been developed to simulate streamflow dynamics in glacieriz

Chronic kidney disease (CKD) is the leading cause of mortality in aged cats. After injury, feline kidneys undergo extensive metabolic reprogramming, but a comprehensive evaluation is lacking. Here we show a multi-omics study including serum metabolomics from 14 healthy control, 15 early stages, 6 late stages CKD cats, and renal cortical and medullary tissue RNA sequencing and proteomics. The analysis reveals a spatiotemporal pattern of gene and protein expression changes. In the early stages, there are 6 di

Alpine glaciers are undergoing rapid mass loss, primarily driven by rising summer air temperatures. However, the glacier microclimate, especially the role of atmospheric dynamics near the surface and turbulent fluxes, is not adequately understood. This study examines the structure and variability of the glacier boundary layer, focusing on katabatic winds and their modulation by synoptic-scale disturbances. Using a high-resolution thermal infrared (TIR) camera (InfraTec VarioCam HD) directed at synthetic scr

The interplay between mechanical forces and genetic programs is fundamental to embryonic development, yet how these factors influence morphogenesis and cell fate decisions remains unclear. Here, we fine-tune the mechanical environment of murine gastruloids, three-dimensional in vitro models of early embryogenesis, by embedding them in bioinert hydrogels with tunable stiffness and timing. This strategy reveals that external constraints can selectively influence transcriptional profiles, patterning or morphol

We are living in an age increasingly shaped by a continuous and constructed condition of emergency. Climate disruption, systemic inequality, forced displacement, and ecological degradation are not anomalies but interwoven dynamics that define the present. Emergency has become foundationalâ an organizing framework that governs how we perceive, inhabit, and respond to a changing world. Architectures of Emergency examines how emergency is not only managed but actively constructedâ with the complicity of arch

Mouse lemurs are the smallest and fastest reproducing primates, as well as one of the most abundant, and they are emerging as a model organism for primate biology, behaviour, health and conservation. Although much has been learnt about their ecology and phylogeny in Madagascar and their physiology, little is known about their cellular and molecular biology. Here we used droplet-based and plate-based single-cell RNA sequencing to create Tabula Microcebus, a transcriptomic atlas of 226,000 cells from 27 mouse

Embryo development entails the formation of anatomical structures with distinct biochemical compositions. Compared with the wealth of knowledge on gene regulation, our understanding of metabolic programs operating during embryogenesis is limited. Mass spectrometry imaging (MSI) has the potential to map the distribution of metabolites across embryo development. Here we established uMAIA, an analytical framework for the joint analysis of large MSI datasets, which enables the construction of multidimensional m

Climate change causes plant species to migrate towards the poles and consequently modify the biodiversity, ecosystems and ecosystem services of their new habitats. In European forests, a large amount of non-native plant species introduced through globalization find suitable conditions to survive and spread. In Southern Switzerland, the invasion success of several non-native evergreen species in natural forests questions the capacity of these species to continue to spread northward, making it necessary to id

Regenerative Architecture is a conscious practice that seeks to create projects that benefit all impacted spheres, whether environmental, social or technical. The main aim is to have a qualitative and positive impact on the environment while bringing all users of the site towards mutually beneficial relationships (human and non-human). The design approach is interdisciplinary and focuses on biodiversity, social needs, and energetic solutions, with the aim of contributing to the reversal of environmental dam

The signature of international commitments such as the Sustainable Development Goals (SDGs) and the COP21 Paris Agreement in 2015 demonstrates a current favourable policy context to address environmental issues. These engagements have been endorsed by the European Union (EU) which also launched complementary strategies such as the one on Circular Economy. Doing so, the EU promotes a transition towards a sustainable, low carbon and circular economy where innovation plays a key role. To monitor progress towar

Annelen Kahl, a post-doc in environmental sciences and engineering at EPFL, will oversee a group of four EPFL students during a three-week stint at a high-tech research station on a Siberian island. She will post updates on the EPFL Out There blog.

The limited supply of fossil fuels and environmental reasons shifted research in industry and academia towards finding their replacements. An important part of these efforts is focused on a sustainable production of the 2nd generation of biofuels. Among many proposed molecules, one of the most prominent fuel candidates is Methyl Ethyl Ketone (MEK). MEK, also referred in the literature as 2-butanone, is the most important commercially produced ketone with a broad application as a solvent for paints and adhes

Infections are one of the most common complications in burn injuries. In severe burns, the wound surface is optimal for microbial proliferation as the exudate is a protein rich environment. Autograft and cultured grafts are the main treatments used nowadays. However, they require a two-step surgical procedure, a collecting step and a grafting step, which slows down the treatment. In order to circumvent this two-step procedure, the CHUV has developed biological bandages made of collagen sheets seeded with fe

More and more marine areas are subjected to depleted-O2 concentration, mainly due to eutrophication induced by human activities. These phenomena affect benthic ecosystems, in particular continental shelves and coastal areas where the renewal of the bottom waters is low and/or the organic matter flux is high. Some species of benthic foraminifera are resistant to this hypoxic/anoxic events, surviving weeks to months without oxygen. One of the species known to survive to such extreme condition is the benthic o

Background Corrinoids are an essential cofactor of reductive dehalogenases, the key enzymes of organohalide respiration (OHR). Dehalobacter restrictus is an obligate OHR bacterium (OHRB) able to conserve energy with tetrachloroethene, but is unable to de novo synthesize corrinoids. Genome analysis of D. restrictus strain PER-K23 however revealed the presence of the complete corrinoid biosynthesis pathway. Objectives The aim of the present study is to understand the corrinoid metabolism of D. restrictus stra

Exploring the genome and ecology of Hydrurus foetidus - the dominant alga in glacier-fed streams

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Capturing the Multi‐Decadal Evolution of Glacier–Permafrost Interactions in a High‐Alpine Environment (Ritord, Western Swiss Alps)

From Complex Targets to General Methods: Celebrating Jieping Zhu's 60th Birthday

Rethinking urban forests as essential infrastructure for resilience, equity, and biodiversity in the current climate emergency

Who can learn from whom? The geography of urban climate evidence

Climate-change impacts on dissolved organic matter in glacier-fed streams

Modeling spatial and temporal streamflow dynamics in a highmountain catchment using the SWAT-GL model

Integrated multi-omics analysis of renal metabolism in domestic cats with spontaneous chronic kidney disease

Characterization of the near-surface air temperature dynamics over glaciers using thermal infrared measurements

Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids

Architectures of Emergency. Sentinel Attentions and Relational Governance in a Rapidly Changing World

A molecular cell atlas of mouse lemur, an emerging model primate

Unified mass imaging maps the lipidome of vertebrate development

Frost as a potential barrier to the invasion of evergreen trees in Southern Switzerland

Regenerative Architecture for the Barracks of Poya

The Role of Research and Innovation for the Transition to a Circular Economy in Europe. Evidence from the Community Innovation Survey 2014

Documenting the effects of climate change in Siberia

Discovery and evaluation of novel pathways for production of methyl ethyl ketone

Study of Antimicrobial Peptide Dendrimers on Wound healing in SKin Tissue Engineering

Feeding behaviour of a benthic species (Ammonia tepida) under oxic and anoxic conditions: TEM-NanoSIMS correlation

Corrinoid auxotrophy in the obligate organohalide-respiring Dehalobacter restrictus strain PER-K23