Publication

Parallel optical coherence tomography in scattering samples using a two-dimensional smart-pixel detector array

Theo Lasser, Boris Clément Karamata, Stéphane Bourquin
2002
Journal Articles

Abstract

Parallel optical coherence tomography in scattering samples is demonstrated using a 58 x 58 smart-pixel detector array. A femtosecond mode-locked Ti:Sapphire laser in combination with a free space Michelson interferometer was employed to achieve 4 mum longitudinal resolution and 9 mum transverse resolution on a 260 x 260 mum field of view. We imaged a resolution target covered by an intralipid solution with different scattering coefficients as well as onion cells. (C) 2002 Published by Elsevier Science B.V.

Official source

https://infoscience.epfl.ch/entities/publication/75fc5973-f446-474f-9ee9-a3d643bae7db

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Theo Lasser, Boris Clément Karamata, Stéphane Bourquin
2002
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/75fc5973-f446-474f-9ee9-a3d643bae7db

About this result

Related concepts (31)

Dynamic light scattering

Dynamic light scattering (DLS) is a technique in physics that can be used to determine the size distribution profile of small particles in suspension or polymers in solution. In the scope of DLS, temporal fluctuations are usually analyzed using the intensity or photon auto-correlation function (also known as photon correlation spectroscopy - PCS or quasi-elastic light scattering - QELS). In the time domain analysis, the autocorrelation function (ACF) usually decays starting from zero delay time, and faster dynamics due to smaller particles lead to faster decorrelation of scattered intensity trace.

Scattering

Scattering is a term used in physics to describe a wide range of physical processes where moving particles or radiation of some form, such as light or sound, are forced to deviate from a straight trajectory by localized non-uniformities (including particles and radiation) in the medium through which they pass. In conventional use, this also includes deviation of reflected radiation from the angle predicted by the law of reflection.

Static light scattering

Static light scattering is a technique in physical chemistry that measures the intensity of the scattered light to obtain the average molecular weight Mw of a macromolecule like a polymer or a protein in solution. Measurement of the scattering intensity at many angles allows calculation of the root mean square radius, also called the radius of gyration Rg. By measuring the scattering intensity for many samples of various concentrations, the second virial coefficient, A2, can be calculated.

Related publications (6)

Parallel optical coherence tomography in scattering samples using a two-dimensional smart-pixel detector array

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