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Anterior-posterior polarity in the Caenorhabditis elegans zygote depends on two groups of PAR proteins, as well as on cortical flow. Recent work now demonstrates that this polarization results from a transition in a bistable reaction-diffusion system of PAR proteins that is triggered by cortical flow.
Anne-Clémence Corminboeuf, Puck Elisabeth van Gerwen, Yannick Calvino Alonso
Véronique Michaud, Jacobus Gerardus Rudolph Staal
Wanda Andreoni, Fabio Pietrucci, Changru Ma