Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency

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Background The spatial organization of the mammalian genome relies upon the formation of chromatin domains of various scales. At the level of gene regulation in cis, collections of enhancer sequences define large regulatory landscapes that usually match wi ...

Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency

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