Publications related to Polymer Nanoparticle-Mediated Delivery of Oxidized Tumor Lysate-Based Cancer Vaccines

Related publications (11)

Deconstructing Precision Electrophile Regulatory Mechanisms in Protease-Mediated Neutrophil Apoptosis

The innate immune system maintains internal homeostasis against hordes of ever-present pathogens. Principally, neutrophils and macrophages are recruites to sites of tissue damage to manage or slow down the rate of infection through several mechanisms, such ...

EPFL2025

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Sofya Mikhaleva, Alexandre Louis André Persat

Biofilm formation is generally recognized as a bacterial defense mechanism against environmental threats, including antibiotics, bacteriophages, and leukocytes of the human immune system. Here, we show that for the human pathogen Vibrio cholerae, biofilm f ...

CELL PRESS2023

Nonlinear Photoluminescence in Gold Thin Films

Sergejs Boroviks

Promisingapplications in photonics are driven by the ability tofabricate crystal-quality metal thin films of controlled thicknessdown to a few nanometers. In particular, these materials exhibit ahighly nonlinear response to optical fields owing to the indu ...

AMER CHEMICAL SOC2023

Advanced technological tools to study multidrug resistance in cancer

Sandor Kasas

The complexity of cancer biology and its clinical manifestation are driven by genetic, epigenetic, transcriptomic, proteomic and metabolomic alterations, supported by genomic instability as well as by environmental conditions and lifestyle factors. Althoug ...

CHURCHILL LIVINGSTONE2020

Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

Francesco Stellacci, Ahmet Bekdemir

We sought to develop a nanoparticle vehicle that could efficiently deliver small molecule drugs to target lymphocyte populations. The synthesized amphiphilic organic ligand-protected gold nanoparticles (amph-NPs) were capable of sequestering large payloads ...

2019

HIV Transmission Chains Exhibit Greater HLA-B Homogeneity Than Randomly Expected

Jacques Fellay, Christian Axel Wandall Thorball

Background: HIV's capacity to escape immune recognition by human leukocyte antigen (HLA) is a core component of HIV pathogenesis. A better understanding of the distribution of HLA class I in HIV-infected patients would improve our knowledge of pathogenesis ...

LIPPINCOTT WILLIAMS & WILKINS2019

Elucidating regulatory mechanisms shaping the transcriptome and proteome of the gut immune response in Drosophila melanogaster

Michael Vincent Frochaux

Work on Drosophila melanogaster paved the way to our current understanding of modern genetics. Since then, this model organism has contributed greatly to various fields such as neurobiology, development, and immunology. The discovery and analysis of the va ...

EPFL2019

Interference of engineered nanomaterials in flow cytometry: A case study

Aurélie Walter

Nanotechnology is regarded as the enabling technology of the 21st century. However, only a relatively small number of nano-enabled medical and healthcare products finally made their way to the market. There are several reasons why such innovative approache ...

ELSEVIER SCIENCE BV2018

The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

Harm-Anton Klok, Cristiana Berti, Michele Graciotti

Background: Immunotherapy consists of activating the patient's immune system to fight cancer and has the great potential of preventing future relapses thanks to immunological memory. A great variety of strategies have emerged to harness the immune system a ...

2017

Highly water soluble trithiolato-bridged dinuclear arene ruthenium complexes

Paul Joseph Dyson, Patrycja Nowak-Sliwinska

Water soluble arene-functionalised trithiolato-bridged ruthenium complexes of general formula (eta(6)-C6H5OCH2CH2OH)(2)Ru-2(mu-SR)(3), where R = C6H5 (1), C6H4-p-OMe (2), C6H4-p-OMe (3), C6H4-p-Pr-i (4), C6H4-p-Bu-t (5), CH2C6H5 (6), CH2CH2C6H5 (7) an ...

Elsevier Science Sa2014

Pathogen-free husbandry conditions alleviate behavioral deficits and neurodegeneration in AD10 anti-NGF mice

Maria del Carmen Sandi Perez, Daniel Constam, Stamatina Tzanoulinou

It has been suggested that systemic infection, occurring during aging and chronic neurodegenerative diseases, can evoke an immune response that aggravates the progression of neurodegeneration and cognitive decline. It has been shown that the AD11 neurodege ...

2014