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Publication

Dependence of the spike-triggered average voltage on membrane response properties

Wulfram Gerstner, Laurent Badel
2006
Journal Articles

Abstract

The spike-triggered average voltage (STV) is an experimentally measurable quantity that is determined by both the membrane response properties and the statistics of the synaptic drive. Here, the form of the STV is modelled for neurons with three distinct types of subthreshold dynamics; passive decay, h-current sag, and damped oscillations. Analytical expressions for the STV are first obtained in the low-noise limit, identifying how the subthreshold dynamics of the cell affect its form. A second result is then derived that captures the power-law behaviour of the STV near the spike threshold.

Official source

https://infoscience.epfl.ch/entities/publication/72043160-61e4-4fa2-b244-596d36bbf79d

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Wulfram Gerstner, Laurent Badel
2006
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/72043160-61e4-4fa2-b244-596d36bbf79d

About this result

Related concepts (31)

Biological neuron model

Biological neuron models, also known as a spiking neuron models, are mathematical descriptions of the properties of certain cells in the nervous system that generate sharp electrical potentials across their cell membrane, roughly one millisecond in duration, called action potentials or spikes (Fig. 2). Since spikes are transmitted along the axon and synapses from the sending neuron to many other neurons, spiking neurons are considered to be a major information processing unit of the nervous system.

Membrane potential

Membrane potential (also transmembrane potential or membrane voltage) is the difference in electric potential between the interior and the exterior of a biological cell. That is, there is a difference in the energy required for electric charges to move from the internal to exterior cellular environments and vice versa, as long as there is no acquisition of kinetic energy or the production of radiation. The concentration gradients of the charges directly determine this energy requirement.

Action potential

An action potential occurs when the membrane potential of a specific cell rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and in some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells.

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Dependence of the spike-triggered average voltage on membrane response properties

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