On the intrahemispheric connectivity of the monkey: a diffusion tractography and tract tracing analysis

In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingulate and parietal areas of the monkey. In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingulate and parietal areas of the monkey. We analyze the agreements between the tractography and the tracing for connected and not connected regions. We report an accuracy of 0.71across all pairs of regions, with twice the number of true positive than false positive connections. Some regions show accuracy higher than 0.80, while other regions show accuracy lower than 0.6. A further analysis of the location of false positive and false negative connections will help understand the limitations and improve diffusion tractography algorithms. We analyze the agreements between the tractography and the tracing for connected and not connected regions. We report an accuracy of 0.71 across all pairs of regions, with twice the number of true positive than false positive connections. Some regions show accuracy higher than 0.80, while other regions show accuracy lower than 0.6. Further analysis of the location of false positive and false negative connections will help understand the limitations and improve diffusion tractography algorithms.