Publication

Revealing chromatin organization in metaphase chromosomes

Beat Fierz
2019
Journal Articles

Abstract

The local structural organization of chromatin in mitotic chromosomes is not well understood. A new cryo-electron tomography study from the Daban laboratory (Chicano et al, ) reveals that mitotic chromatin isolated from human cells can assume a plate-like fine structure, containing layers of interdigitated nucleosomes. Such a multilayered organization suggests a possible model for mitotic chromatin compaction.

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Revealing chromatin organization in metaphase chromosomes

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