A platform for experimental precision medicine: The extended BXD mouse family

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Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the ...

Background Alzheimer's disease (AD) is a complex disorder caused by a combination of genetic and non-genetic risk factors. In addition, an increasing evidence suggests that epigenetic mechanisms also accompany AD. Genetic and epigenetic factors are not ind ...

Background: Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understan ...

Global increase in the human population and life-style changes have led to enormous development in various industries, including beverage industry. Among the innumerable beverage industries, wineries have received increasing attention and consideration due ...

Development of novel analytical devices complying with modern requirements of simplicity and cost-effectiveness is an important task. Multisensor systems based on various types of chemical sensors are promising tools in this respect. Herein the development ...

We report the molecular basis of the largest Tunisian cohort with inherited retinal dystrophies (IRD) reported to date, identify disease-causing pathogenic variants and describe genotype-phenotype correlations. A subset of 26 families from a cohort of 73 f ...

In this work, we resolve a big challenge that most current image quality metrics (IQMs) are unavailable across different image contents, especially simultaneously coping with natural scene (NS) images or screen content (SC) images. By comparison with exist ...

Social, economic and environmental phenomena as well as the presence of groups of stakeholders with diverging and contradictory interests highlight the complexity of urban projects. Traditional instruments of urban management are seldom adapted to these ch ...

A platform for experimental precision medicine: The extended BXD mouse family

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A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

Comprehensive analysis of PM20D1 QTL in Alzheimer's disease

cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel

Critical review on bioconversion of winery wastes into value-added products

Cyclometalated Ir(III) complexes as tuneable multiband light sources for optical multisensor systems: Feasibility study

Genetic spectrum of retinal dystrophies in Tunisia

Learning a Unified Blind Image Quality Metric via On-Line and Off-Line Big Training Instances

Approche systémique et participative du diagnostic urbain : processus de représentation cognitive du système urbain en vue de l'élaboration d'indicateurs géographiques