Granulysin Antimicrobial Activity Promotes Dormancy in Mycobacterium tuberculosis

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An antimicrobial activity screen of Burkholderia gladioli BCC0238, a clinical isolate from a cystic fibrosis patient, led to the discovery of gladiolin, a novel macrolide antibiotic with potent activity against Mycobacterium tuberculosis H37Rv. Gladiolin i ...

Nitroarenes are less preferred in drug discovery due to their potential to be mutagenic. However, several nitroarenes were shown to be promising antitubercular agents with specific modes of action, namely, nitroimidazoles and benzothiazinones. The nitro gr ...

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Granulysin Antimicrobial Activity Promotes Dormancy in Mycobacterium tuberculosis

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Amperometric Urine Biosensor for Rapid Point-of-Care Tuberculosis Diagnosis

Spatially Controlled Activation of Toll-like Receptor 9 with DNA-Based Nanomaterials

Preclinical development of a humanized chimeric antigen receptor against B-cell maturation antigen for multiple myeloma

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes

Label-free plasmonic biosensors for real-time live cell analysis

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

Investigating the Biological Mechanisms underlying the Initiation of Autoimmunity against Beta Cell Antigens in Type 1 Diabetes

Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis

Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity

Kinase Regulation in Mycobacterium tuberculosis: Variations on a Theme

Simple and Rapid Method To Determine Antimycobacterial Potency of Compounds by Using Autoluminescent Mycobacterium tuberculosis

Inhibition of Sepiapterin Reductase through Formation of a Ternary Complex with Sulfasalazine or other Sulfa Drugs and NADP+