Publication

Target of rapamycin modulators of and use thereof

Yann Barrandon, Fahd Azzabi Zouraq
2009
Patents

Abstract

The present invention is related to new molecules capable of interacting with target of rapamycin (TOR) transcriptional complex. In particular, the present invention provides novel nucleic acid molecules, processes for production thereof, kits containing thereof, use of these in an assay for the identification of mammalian target of rapamycin (mTOR) modulators, use of mammalian target of rapamycin (mTOR) modulators identified by this assay for the preparation of a formulation for the control of hair growth and compositions for the control of hair growth.

Official source

https://infoscience.epfl.ch/entities/publication/6e2a3afb-f4f3-4fb4-96ac-f2e0ae5e7f7a

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Yann Barrandon, Fahd Azzabi Zouraq
2009
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/6e2a3afb-f4f3-4fb4-96ac-f2e0ae5e7f7a

About this result

Related concepts (32)

MTOR

The 'mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin', and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene. mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component of two distinct protein complexes, mTOR complex 1 and mTOR complex 2, which regulate different cellular processes.

Assay

An assay is an investigative (analytic) procedure in laboratory medicine, mining, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity. The measured entity is often called the analyte, the measurand, or the target of the assay. The analyte can be a drug, biochemical substance, chemical element or compound, or cell in an organism or organic sample.

Formulation

Formulation is a term used in various senses in various applications, both the material and the abstract or formal. Its fundamental meaning is the putting together of components in appropriate relationships or structures, according to a formula. Etymologically formula is the diminutive of the Latin forma, meaning shape. In that sense a formulation is created according to the standard for the product. Disciplines in which one might use the word formulation in the abstract sense include logic, mathematics, linguistics, legal theory, and computer science.

Related publications (28)

Target of rapamycin modulators of and use thereof

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