Publications related to Laminar analysis of the cerebellar cortex shows widespread damage in early MS patients: A pilot study at 7T MRI

Related publications (18)

Coupled Electromagnetic-Electrophysiological Modeling of Neural Circuits

Much of our knowledge about the brain is derived from extracellular recordings of the electric fields produced by neural activity. However, interpretation of these signals is nontrivial. In par- ticular, it is difficult to link macro-scale observations of ...

EPFL2024

Direct stimulation of anterior insula and ventromedial prefrontal cortex disrupts economic choices

Antoine Collomb-Clerc

Neural activity within the ventromedial prefrontal cortex (vmPFC) and anterior insula (aIns) is often associated with economic choices and confidence. However, it remains unclear whether these brain regions are causally related to these processes. To addre ...

NATURE PORTFOLIO2024

Structured cerebellar connectivity supports resilient pattern separation

Ilaria Ricchi

The cerebellum is thought to help detect and correct errors between intended and executed commands(1,2) and is critical for social behaviours, cognition and emotion 3 Computations for motor control must be performed quicklyto correct errors in real time an ...

NATURE PORTFOLIO2023

Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper

Traian Popa

Transcranial (electro)magnetic stimulation (TMS) is currently the method of choice to non-invasively induce neural activity in the human brain. A single transcranial stimulus induces a time-varying electric field in the brain that may evoke action potentia ...

ELSEVIER IRELAND LTD2022

What Makes for Automatic Reconstruction of Pulmonary Segments

Li Zhang, Jiancheng Yang

3D reconstruction of pulmonary segments plays an important role in surgical treatment planning of lung cancer, which facilitates preservation of pulmonary function and helps ensure low recurrence rates. However, automatic reconstruction of pulmonary segmen ...

SPRINGER INTERNATIONAL PUBLISHING AG2022

NeuralTree: A 256-Channel 0.227-mu J/Class Versatile Neural Activity Classification and Closed-Loop Neuromodulation SoC

Stéphanie Lacour, Mahsa Shoaran, Bingzhao Zhu, Uisub Shin, Alix Esther Anne Trouillet, Cong Ding, Emilie Cornelia Maria Revol, Yashwanth Sai Reddy Vyza

Closed-loop neural interfaces with on-chip machine learning can detect and suppress disease symptoms in neurological disorders or restore lost functions in paralyzed patients. While high-density neural recording can provide rich neural activity information ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging

Meritxell Bach Cuadra, Francesco La Rosa

Damage to the myelin sheath and the neuroaxonal unit is a cardinal feature of multiple sclerosis; however, a detailed characterization of the interaction between myelin and axon damage in vivo remains challenging. ...

OXFORD UNIV PRESS2021

Brain network modulation in transradial amputee with finger perception restored through biomimetic intraneural stimulation

Silvestro Micera, Giacomo Valle, Fabrizio Vecchio

Introduction/aims The hand is a sophisticated tool which allows humans to interact with the external world mainly via the sense of touch. Previous evidences demonstrated that electrical stimulations of the nerve trunks governing the hand are able to restor ...

SPRINGER-VERLAG ITALIA SRL2021

Glutaredoxin 1 Downregulation in the Substantia Nigra Leads to Dopaminergic Degeneration in Mice

Bernard Schneider

Background Parkinson's disease (PD) is characterized by a severe loss of the dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). Perturbation of protein thiol redox homeostasis has been shown to play a role in the dysregulation of cell ...

2020

Longitudinal study of neonatal brain tissue volumes in preterm infants and their ability to predict neurodevelopmental outcome

Djalel Eddine Meskaldji, Serafeim Loukas

Premature birth has been associated with poor neurodevelopmental outcomes. However, the relation between such outcomes and brain growth in the neonatal period has not yet been fully elucidated. This study investigates longitudinal brain development between ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

Robust Recovery of Temporal Overlap Between Network Activity Using Transient-Informed Spatio-Temporal Regression

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton, Marie Schaer, Daniela Maria Zöller, Fikret Isik Karahanoglu

Functional magnetic resonance imaging is a non-invasive tomographic imaging modality that has provided insights into system-level brain function. New analysis methods are emerging to study the dynamic behavior of brain activity. The innovation-driven co-ac ...

Institute of Electrical and Electronics Engineers2019

Whole Genome Sequence Analysis Of A Cousin Pair With Restricting Anorexia Nervosa

Pierre Magistretti

ELSEVIER SCIENCE BV2019

Decoding the 'Spectral Diet'

Marilyne Andersen, Forrest Simon Webler

KARGER2019

Microfluidic-based immunohistochemistry for breast cancer diagnosis: a comparative clinical study

Fabio Aimi, Martinus Adela Maria Gijs, Diego Gabriel Dupouy, Saska Brajkovic

Breast cancer is a highly heterogeneous disease. The efficacy of tailored therapeutic strategies relies on the precise detection of diagnostic biomarkers by immunohistochemistry (IHC). Therefore, considering the increasing incidence of breast cancer cases, ...

2019

Cortical Dysconnectivity Measured by Structural Covariance Is Associated With the Presence of Psychotic Symptoms in 22q11.2 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Marie Schaer, Maude Schneider

BACKGROUND: 22q11.2 deletion syndrome (22q11DS) is the third-largest known genetic risk factor for the development of psychosis. Dysconnectivity has consistently been implicated in the physiopathology of psychosis. Structural covariance of cortical morphol ...

2018

Parallel pathways from whisker and visual sensory cortices to distinct frontal regions of mouse neocortex

Carl Petersen, Varun Sreenivasan, Céline Matéo, Alexandros Kyriakatos

The spatial organization of mouse frontal cortex is poorly understood. Here, we used voltage-sensitive dye to image electrical activity in the dorsal cortex of awake head-restrained mice. Whisker-deflection evoked the earliest sensory response in a localiz ...

SPIE-Intl Soc Optical Eng2017

Microcircuits in action--from CPGs to neocortex

Henry Markram, Gilad Silberberg

To understand the interface between global brain function and molecular neuroscience--that is, the microcircuit level--a major challenge. Such understanding is prerequisite if we are to account for neural function in cellular terms. Very few vertebrate mic ...

2005

Selective postsynaptic co-localization of MCT2 with AMPA receptor GluR2/3 subunits at excitatory synapses exhibiting AMPA receptor trafficking

Pierre Magistretti

MCT2 is the main neuronal monocarboxylate transporter needed by neurons if they are to use lactate as an additional energy substrate. Previous evidence suggested that some MCT2 could be located in postsynaptic elements of glutamatergic synapses. Using post ...

2005