Publication

Recombinant bacteria resistant to horizontal gene transfer and phage infection

Melanie Blokesch, David William Adams, Milena Jadwiga Jaskolska
2023
Patents

Abstract

The invention relates to an expression vector encoding a DNA defence system comprising polypeptides derived from Vibrio cholerae, or equivalent functional variants or homologues, conferring resistance to the maintenance of extra-genomic DNA to a recipient bacterial cell. The invention further relates to methods for obtaining an isolated bacterium, or a bacterial population capable of eliminating extra-genomic DNA, or of protecting against phage infection, and an isolated bacterium, or a product comprising an expression vector according to the invention.

Official source

https://infoscience.epfl.ch/entities/publication/6784e763-b332-41c2-bb65-87f48833b8db

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Recombinant bacteria resistant to horizontal gene transfer and phage infection

Chat with Graph Search

Update on Interfacial Charge Transfer (IFTC) Processes on Films Inactivating Viruses/Bacteria under Visible Light: Mechanistic Considerations and Critical Issues

Recent advances on sputtered films with Cu in ppm concentrations leading to an acceleration of the bacterial inactivation

Tetrahydrobiopterin Biosynthesis as an Off-Target of Sulfa Drugs