Publication

A Surface-based approach to Quantify Local Cortical Gyrification

Jean-Philippe Thiran, Meritxell Bach Cuadra
2008
Journal Articles

Abstract

The high complexity of cortical convolutions in humans remains a mystery for both engineers to measure and compare it, and for biologists to understand it. We developed a method for the quantification of the cortical area allowed by the process of folding. Our method uses accurate three-dimensional cortical reconstruction and compute local measurements of gyrification at thousands of points over the whole cortical surface. The potential of our method to identify and localize subregional gyrification abnormalities is illustrated by a clinical study on a group of children affected by 22q11 Deletion Syndrome compared to control individuals.

Official source

https://infoscience.epfl.ch/entities/publication/66607e26-4ce2-431d-8d40-0b2d2d382de1

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Jean-Philippe Thiran, Meritxell Bach Cuadra
2008
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/66607e26-4ce2-431d-8d40-0b2d2d382de1

About this result

Related concepts (32)

Cerebral cortex

The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system.

Cortical column

A cortical column is a group of neurons forming a cylindrical structure through the cerebral cortex of the brain perpendicular to the cortical surface. The structure was first identified by Mountcastle in 1957. He later identified minicolumns as the basic units of the neocortex which were arranged into columns. Each contains the same types of neurons, connectivity, and firing properties. Columns are also called hypercolumn, macrocolumn, functional column or sometimes cortical module.

Cortical stimulation mapping

Cortical stimulation mapping (CSM) is a type of electrocorticography that involves a physically invasive procedure and aims to localize the function of specific brain regions through direct electrical stimulation of the cerebral cortex. It remains one of the earliest methods of analyzing the brain and has allowed researchers to study the relationship between cortical structure and systemic function.

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A Surface-based approach to Quantify Local Cortical Gyrification

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