Publications related to A maturational shift in the frontal cortex synaptic transcriptional landscape underlies schizophrenia-relevant behavioural traits: A congenital rat model

Related publications (13)

Understanding hormone signaling and its risk on estrogen receptor-positive breast cancer

Next generation sequencing (NGS), in vivo models, and drug screening reshaped research. In breast cancer, transcriptomics plays an important role in subtyping the disease. In vivo models are used to better understand the disease and drug screenings are use ...

EPFL2024

Higher-order connectomics of human brain function reveals local topological signatures of task decoding, individual identification, and behavior

Enrico Amico, Andrea Santoro

Traditional models of human brain activity often represent it as a network of pairwise interactions between brain regions. Going beyond this limitation, recent approaches have been proposed to infer higher-order interactions from temporal brain signals inv ...

Nature Portfolio2024

A neurometabolic mechanism involving dmPFC/dACC lactate in physical effort-based decision-making

Maria del Carmen Sandi Perez, Lijing Xin, Arthur Barakat, Nicolas Clairis

Motivation levels vary across individuals, yet the underlying mechanisms driving these differences remain elusive. The dorsomedial prefrontal cortex/dorsal anterior cingulate cortex (dmPFC/dACC) and the anterior insula (aIns) play crucial roles in effort-b ...

Springer Science and Business Media LLC2024

In vivo parcellation of the human spinal cord functional architecture

Dimitri Nestor Alice Van De Ville, Nawal Noëlle Kinany

The spinal cord is a critical component of the central nervous system, transmitting and integrating signals between the brain and the periphery via topographically organized functional levels. Despite its central role in sensorimotor processes and several ...

2024

Plasticity of sensory representations in the posterior insular cortex during fear learning

Denys Osypenko

Aversively-motivated associative learning allows animals to avoid harm and thus ensures survival. Aversive learning can be studied by the fear learning paradigm, in which an innocuous sensory stimulus like a tone (conditioned stimulus, CS), acquires a nega ...

EPFL2023

Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics

Rebecca Carolyn Smith

Neuronal endoplasmic reticulum (ER) appears continuous throughout the cell. Its shape and continuity are influenced by ER-shaping proteins, mutations in which can cause distal axon degeneration in Hereditary Spastic Paraplegia (HSP). We therefore asked how ...

Rockefeller University Press2023

Integrative transcriptome analyses of Transposable Elements (TEs) and genes contribute to a better understanding of colorectal cancer

Eunji Shin

Cancer is the second leading cause of death worldwide. Cancer develops through multiple hallmark functions including apoptosis evasion, unlimited replicative potential, metastasis, and immune avoidance. Over the past few decades, researchers have reported ...

EPFL2022

An Epigenetic Contribution to Neuronal Competition During Memory Allocation

Liliane Glauser, Giulia Santoni

SPRINGERNATURE2021

The Clustering of mApoE Anti-Amyloidogenic Peptide on Nanoparticle Surface Does Not Alter Its Performance in Controlling Beta-Amyloid Aggregation

Francesco Stellacci, Paulo Henrique Jacob Silva

The deposition of amyloid-beta (A beta) plaques in the brain is a significant pathological signature of Alzheimer's disease, correlating with synaptic dysfunction and neurodegeneration. Several compounds, peptides, or drugs have been designed to redirect o ...

2020

EEG microstates are a candidate endophenotype for schizophrenia

Michael Herzog, Maya Roinishvili, Christine Mohr, Patricia Figueiredo, Janir Nuno Ramos Antunes Da Cruz, Ophélie Gladys Favrod

Electroencephalogram microstates are recurrent scalp potential configurations that remain stable for around 90 ms. The dynamics of two of the four canonical classes of microstates, commonly labeled as C and D, have been suggested as a potential endophenoty ...

Nature Research2020

Music processing in preterm and full-term newborns: A psychophysiological interaction (PPI) approach in neonatal fMRI

Dimitri Nestor Alice Van De Ville, François Lazeyras, Serafeim Loukas

Neonatal Intensive Care Units (NICU) provide special equipment designed to give life support for the increasing number of prematurely born infants and assure their survival. More recently NICU's strive to include developmentally oriented care and modulate ...

2019

Axonal and myelin injury in white matter and cortex of relapsing-remitting and progressive multiple sclerosis patients: a combined myelin water and multi-shell diffusion MRI study

Yi Wang, Meritxell Bach Cuadra, Cristina Granziera, Francesco La Rosa

SAGE PUBLICATIONS LTD2019

Breaking the Fourth Wall: Modulating Quaternary Associations for Protein Regulation and Drug Discovery

Yimon Aye, Bokyoung Kim

Protein-protein interactions (PPIs) are an effective means to orchestrate intricate biological processes required to sustain life. Approximately 650000 PPIs underlie the human interactome; thus underscoring its complexity and the manifold signaling outputs ...

WILEY-V C H VERLAG GMBH2019