Neural circuitA neural circuit (also known as a biological neural network BNNs) is a population of neurons interconnected by synapses to carry out a specific function when activated. Multiple neural circuits interconnect with one another to form large scale brain networks. Neural circuits have inspired the design of artificial neural networks, though there are significant differences. Early treatments of neural networks can be found in Herbert Spencer's Principles of Psychology, 3rd edition (1872), Theodor Meynert's Psychiatry (1884), William James' Principles of Psychology (1890), and Sigmund Freud's Project for a Scientific Psychology (composed 1895).
Neural oscillationNeural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons.
SchizophreniaSchizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, and flat affect. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a psychiatric history that includes the person's reported experiences, and reports of others familiar with the person.
Models of neural computationModels of neural computation are attempts to elucidate, in an abstract and mathematical fashion, the core principles that underlie information processing in biological nervous systems, or functional components thereof. This article aims to provide an overview of the most definitive models of neuro-biological computation as well as the tools commonly used to construct and analyze them.
Line (geometry)In geometry, a line is an infinitely long object with no width, depth, or curvature. Thus, lines are one-dimensional objects, though they may exist embedded in two, three, or higher dimensional spaces. The word line may also refer to a line segment in everyday life that has two points to denote its ends (endpoints). A line can be referred to by two points that lie on it (e.g. ) or by a single letter (e.g. ).
Artificial neural networkArtificial neural networks (ANNs, also shortened to neural networks (NNs) or neural nets) are a branch of machine learning models that are built using principles of neuronal organization discovered by connectionism in the biological neural networks constituting animal brains. An ANN is based on a collection of connected units or nodes called artificial neurons, which loosely model the neurons in a biological brain. Each connection, like the synapses in a biological brain, can transmit a signal to other neurons.
Pencil (geometry)In geometry, a pencil is a family of geometric objects with a common property, for example the set of lines that pass through a given point in a plane, or the set of circles that pass through two given points in a plane. Although the definition of a pencil is rather vague, the common characteristic is that the pencil is completely determined by any two of its members. Analogously, a set of geometric objects that are determined by any three of its members is called a bundle.
Euler lineIn geometry, the Euler line, named after Leonhard Euler (ˈɔɪlər), is a line determined from any triangle that is not equilateral. It is a central line of the triangle, and it passes through several important points determined from the triangle, including the orthocenter, the circumcenter, the centroid, the Exeter point and the center of the nine-point circle of the triangle. The concept of a triangle's Euler line extends to the Euler line of other shapes, such as the quadrilateral and the tetrahedron.
CoplanarityIn geometry, a set of points in space are coplanar if there exists a geometric plane that contains them all. For example, three points are always coplanar, and if the points are distinct and non-collinear, the plane they determine is unique. However, a set of four or more distinct points will, in general, not lie in a single plane. Two lines in three-dimensional space are coplanar if there is a plane that includes them both. This occurs if the lines are parallel, or if they intersect each other.
Schizotypal personality disorderSchizotypal personality disorder (StPD or SPD), also known as schizotypal disorder, is a cluster A personality disorder. The Diagnostic and Statistical Manual of Mental Disorders (DSM) classification describes the disorder specifically as a personality disorder characterized by thought disorder, paranoia, a characteristic form of social anxiety, derealization, transient psychosis, and unconventional beliefs.
PsychosisPsychosis is a condition of the mind that results in difficulties determining what is real and what is not real. Symptoms may include delusions and hallucinations, among other features. Additional symptoms are incoherent speech and behavior that is inappropriate for a given situation. There may also be sleep problems, social withdrawal, lack of motivation, and difficulties carrying out daily activities. Psychosis can have serious adverse outcomes. As with many psychiatric phenomena, psychosis has several different causes.
Reelin'Reelin', encoded by the RELN gene, is a large secreted extracellular matrix glycoprotein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell–cell interactions. Besides this important role in early development, reelin continues to work in the adult brain. It modulates synaptic plasticity by enhancing the induction and maintenance of long-term potentiation.
Lunatic asylumThe lunatic asylum or insane asylum was an early precursor of the modern psychiatric hospital. The fall of the lunatic asylum and its eventual replacement by modern psychiatric hospitals explains the rise of organized, institutional psychiatry. While there were earlier institutions that housed the "insane", the conclusion that institutionalization was the correct solution to treating people considered to be "mad" was part of a social process in the 19th century that began to seek solutions outside of families and local communities.
Incidence geometryIn mathematics, incidence geometry is the study of incidence structures. A geometric structure such as the Euclidean plane is a complicated object that involves concepts such as length, angles, continuity, betweenness, and incidence. An incidence structure is what is obtained when all other concepts are removed and all that remains is the data about which points lie on which lines. Even with this severe limitation, theorems can be proved and interesting facts emerge concerning this structure.
Dopamine hypothesis of schizophreniaThe dopamine hypothesis of schizophrenia or the dopamine hypothesis of psychosis is a model that attributes the positive symptoms of schizophrenia to a disturbed and hyperactive dopaminergic signal transduction. The model draws evidence from the observation that a large number of antipsychotics have dopamine-receptor antagonistic effects. The theory, however, does not posit dopamine overabundance as a complete explanation for schizophrenia.
Insulin shock therapyInsulin shock therapy or insulin coma therapy was a form of psychiatric treatment in which patients were repeatedly injected with large doses of insulin in order to produce daily comas over several weeks. It was introduced in 1927 by Austrian-American psychiatrist Manfred Sakel and used extensively in the 1940s and 1950s, mainly for schizophrenia, before falling out of favour and being replaced by neuroleptic drugs in the 1960s. It was one of a number of physical treatments introduced into psychiatry in the first four decades of the 20th century.
SchizotypyIn psychology, schizotypy is a theoretical concept that posits a continuum of personality characteristics and experiences, ranging from normal dissociative, imaginative states to extreme states of mind related to psychosis, especially schizophrenia. The continuum of personality proposed in schizotypy is in contrast to a categorical view of psychosis, wherein psychosis is considered a particular (usually pathological) state of mind, which the person either has or does not have.
Fano planeIn finite geometry, the Fano plane (after Gino Fano) is a finite projective plane with the smallest possible number of points and lines: 7 points and 7 lines, with 3 points on every line and 3 lines through every point. These points and lines cannot exist with this pattern of incidences in Euclidean geometry, but they can be given coordinates using the finite field with two elements. The standard notation for this plane, as a member of a family of projective spaces, is PG(2, 2).
PatientA patient is any recipient of health care services that are performed by healthcare professionals. The patient is most often ill or injured and in need of treatment by a physician, nurse, optometrist, dentist, veterinarian, or other health care provider. The word patient originally meant 'one who suffers'. This English noun comes from the Latin word patiens, the present participle of the deponent verb, patior, meaning 'I am suffering,' and akin to the Greek verb πάσχειν (paskhein, to suffer) and its cognate noun πάθος (pathos).
Intersection (geometry)In geometry, an intersection is a point, line, or curve common to two or more objects (such as lines, curves, planes, and surfaces). The simplest case in Euclidean geometry is the line–line intersection between two distinct lines, which either is one point or does not exist (if the lines are parallel). Other types of geometric intersection include: Line–plane intersection Line–sphere intersection Intersection of a polyhedron with a line Line segment intersection Intersection curve Determination of the intersection of flats – linear geometric objects embedded in a higher-dimensional space – is a simple task of linear algebra, namely the solution of a system of linear equations.
