Publication

Low- to high-throughput analysis of telomerase modulators with Telospot

Joachim Lingner, Gerardo Turcatti, Marc Chambon
2007
Journal Articles

Abstract

We designed a method termed Telospot to discover and characterize telomerase modulators as anticancer drugs or chemical biology tools. Telospot is based on a highly efficient human telomerase expression system and the detection of telomerase DNA reaction products in macroarray format. Telospot offers a highly scalable, cost- and time-effective alternative to presently available telomerase assays, which are limited by the requirement for PCR, telomerase purification or technologies not amenable to high throughput.

Official source

https://infoscience.epfl.ch/entities/publication/62cd60fa-2220-41de-9795-bf91cc7092c9

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Low- to high-throughput analysis of telomerase modulators with Telospot

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