High-throughput nanoimmunoassay chip

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Related publications (30)

Latchable microfluidic valve arrays based on shape memory polymer actuators

We report arrays of latching microfluidic valves based on shape memory polymers (SMPs), and show their applications as reagent mixers and as peristaltic pumps. The valve design takes advantage of the SMP's multiple stable shapes and over a hundred-fold sti ...

2019

Field-effect transistor device or sensor for sensing ions, molecules or biomarkers in a fluid

Mihai Adrian Ionescu, Erick Antonio Garcia Cordero, Junrui Zhang, Francesco Bellando

The present disclosure concerns a Field-Effect Transistor device or sensor comprising at least one drain region, at least one source region, at least a channel region, at least a first gate connected to the channel region, at least one stack comprising at ...

2019

Microfluidic and micromechanical in vivo studies of Caenorhabditis elegans

Roger Philippe Krenger

Caenorhabditis elegans is one of the most attractive model organisms in biomedical research for understanding human diseases and for drug testing at a whole-organism level, since many biological pathways and genes have been conserved between itself and hum ...

EPFL2019

Transient current technique for charged traps detection in silicon bonded interfaces

Didier Bouvet, Jean-Michel Sallese, Alessandro Mapelli

Wafer bonding is an established technology for the manufacturing of silicon-on-insulator (SOI) substrates, microelectromechanical systems (MEMS) and microfluidic devices. Low temperature direct bonding techniques can be of particular interest for the fabri ...

2019

Reliable and Robust Cyber-Physical Systems for Real-Time Control of Electric Grids

Wajeb Saab

Real-time control of electric grids is a novel approach to handling the increasing penetration of distributed and volatile energy generation brought about by renewables. Such control occurs in cyber-physical systems (CPSs), in which software agents maintai ...

EPFL2019

Label-free plasmonic biosensors for real-time live cell analysis

Xiaokang Li

For decades, the understanding of life has been focused on its most fundamental building blocks: molecules. Deciphering the dynamic activities of protein molecules in human cells is of vital significance for fundamental and clinical studies. The minuscule ...

EPFL2019

Engineered Lateral Roughness Element Implementation and Working Fluid Alteration to Intensify Hydrodynamic Cavitating Flows on a Chip for Energy Harvesting

Luis Guillermo Villanueva Torrijo, Morteza Ghorbani

Hydrodynamic cavitation is considered an effective tool to be used in different applications, such as surface cleaning, ones in the food industry, energy harvesting, water treatment, biomedical applications, and heat transfer enhancement. Thus, both charac ...

2019

Microfluidic-based immunohistochemistry for breast cancer diagnosis: a comparative clinical study

Martinus Gijs, Diego Gabriel Dupouy, Saska Brajkovic, Fabio Aimi

Breast cancer is a highly heterogeneous disease. The efficacy of tailored therapeutic strategies relies on the precise detection of diagnostic biomarkers by immunohistochemistry (IHC). Therefore, considering the increasing incidence of breast cancer cases, ...

2019

Microfluidic device for real-time formulation of reagents and their subsequent encapsulation into double emulsions

Sebastian Maerkl, Esther Amstad, Zoe Newell Swank, Jui-Chia Chang

Emulsion drops are often employed as picoliter-sized containers to perform screening assays. These assays usually entail the formation of drops encompassing discrete objects such as cells or microparticles and reagents to study interactions between the dif ...

Nature Research2018

Lab-on-a-chip technologies for manipulation and imaging of C. elegans worms and embryos

Li Dong

The nematode Caenorhabditis elegans is an attractive model organism, owing notably to its short life cycle, genetic tractability, and optical transparency facilitating microscopic observation. This thesis deals with the realization of technological tools f ...

EPFL2018

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