Small moleculeIn molecular biology and pharmacology, a small molecule or micromolecule is a low molecular weight (≤ 1000 daltons) organic compound that may regulate a biological process, with a size on the order of 1 nm. Many drugs are small molecules; the terms are equivalent in the literature. Larger structures such as nucleic acids and proteins, and many polysaccharides are not small molecules, although their constituent monomers (ribo- or deoxyribonucleotides, amino acids, and monosaccharides, respectively) are often considered small molecules.
Protein–protein interactionProtein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect. Many are physical contacts with molecular associations between chains that occur in a cell or in a living organism in a specific biomolecular context. Proteins rarely act alone as their functions tend to be regulated.
Safari (web browser)Safari is a web browser developed by Apple. It is built into Apple's operating systems, including macOS, iOS, and iPadOS, and uses Apple's open-source browser engine WebKit, which was derived from KHTML. Safari was introduced in Mac OS X Panther in January 2003. It was included with the iPhone since the latter's first generation, which came out in 2007. At that time, Safari was the fastest browser on the Mac. Between 2007 and 2012, Apple maintained a Windows version, but abandoned it due to low market share.
D-moduleIn mathematics, a D-module is a module over a ring D of differential operators. The major interest of such D-modules is as an approach to the theory of linear partial differential equations. Since around 1970, D-module theory has been built up, mainly as a response to the ideas of Mikio Sato on algebraic analysis, and expanding on the work of Sato and Joseph Bernstein on the Bernstein–Sato polynomial. Early major results were the Kashiwara constructibility theorem and Kashiwara index theorem of Masaki Kashiwara.
Molecular phylogeneticsMolecular phylogenetics (məˈlɛkjᵿlər_ˌfaɪloʊdʒəˈnɛtɪks,_mɒ-,_moʊ-) is the branch of phylogeny that analyzes genetic, hereditary molecular differences, predominantly in DNA sequences, to gain information on an organism's evolutionary relationships. From these analyses, it is possible to determine the processes by which diversity among species has been achieved. The result of a molecular phylogenetic analysis is expressed in a phylogenetic tree.
Protein function predictionProtein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. These proteins are usually ones that are poorly studied or predicted based on genomic sequence data. These predictions are often driven by data-intensive computational procedures. Information may come from nucleic acid sequence homology, gene expression profiles, protein domain structures, text mining of publications, phylogenetic profiles, phenotypic profiles, and protein-protein interaction.
Chromium (web browser)Chromium is a free and open-source web browser project, mainly developed and maintained by Google. This codebase provides the vast majority of code for the Google Chrome browser, which is proprietary software and has some additional features. Chromium's logo is identical in shape to that of Google Chrome, but with blue colors instead of being multicolor. The Chromium codebase is widely used. Microsoft Edge, Samsung Internet, Opera, and many other browsers are based on the Chromium code.
Private browsingPrivate browsing is a privacy feature in some web browsers. When operating in such a mode, the browser creates a temporary session that is isolated from the browser's main session and user data. Browsing history is not saved, and local data associated with the session, such as Cookies, Web cache, are cleared when the session is closed. These modes are designed primarily to prevent data and history associated with a particular browsing session from persisting on the device, or being discovered by another user of the same device.
Mammal classificationMammalia is a class of animal within the phylum Chordata. Mammal classification has been through several iterations since Carl Linnaeus initially defined the class. No classification system is universally accepted; McKenna & Bell (1997) and Wilson & Reader (2005) provide useful recent compendiums. Many earlier ideas from Linnaeus et al. have been completely abandoned by modern taxonomists, among these are the idea that bats are related to birds or that humans represent a group outside of other living things.
Stem cellIn multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type.
OrganismAn organism () is any biological living system that functions as an individual life form. All organisms are composed of cells (cell theory). The idea of organism is based on the concept of minimal functional unit of life. Three traits have been proposed to play the main role in qualification as an organism: noncompartmentability – structure that cannot be divided without its functionality loss, individuality – the entity has simultaneous holding of genetic uniqueness, genetic homogeneity and autonomy, distinctness – genetic information has to maintain open-system (a cell).
Stem-cell therapyStem-cell therapy is the use of stem cells to treat or prevent a disease or condition. , the only established therapy using stem cells is hematopoietic stem cell transplantation. This usually takes the form of a bone-marrow transplantation, but the cells can also be derived from umbilical cord blood. Research is underway to develop various sources for stem cells as well as to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes and heart disease.