Publication

Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results

Hubert van den Bergh, Georges Wagnières
1995
Conference Papers

Abstract

Clinical results obtained endoscopically with an imaging fluorescence photodetection apparatus based on the use of one excitation wavelength and detection of the fluorescence emission performed in two separate spectral windows are presented. Early cancer photodetection of micro-invasive and in situ carcinoma of the bronchial mucosa after intravenous injection of meso-tetrahydroxyphenylchlorin (m-THPC) was performed during sessions involving photodynamic therapy. Preliminary results are also presented in the context of detecting transitional cell carcinoma of the bladder performed by fluorescence imaging photodetection of protoporphyrin IX (PPIX) following topical application of 5-delta aminolevulinic acid (ALA).

Official source

https://infoscience.epfl.ch/entities/publication/60325d9a-e8f3-4fe4-bbad-5326f2780120

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Hubert van den Bergh, Georges Wagnières
1995
Conference Papers

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/60325d9a-e8f3-4fe4-bbad-5326f2780120

About this result

Related concepts (32)

Carcinoma

Carcinoma is a malignancy that develops from epithelial cells. Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesodermal or ectodermal germ layer during embryogenesis. Carcinomas occur when the DNA of a cell is damaged or altered and the cell begins to grow uncontrollably and become malignant. It is from the καρκίνωμα (itself derived from karkinos meaning crab).Oxford English Dictionary, 3rd edition, s.

Squamous-cell carcinoma

Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts.

Transitional cell carcinoma

Transitional cell carcinoma, also called urothelial carcinoma, is a type of cancer that typically occurs in the urinary system. It is the most common type of bladder cancer and cancer of the ureter, urethra, and urachus. It accounts for 95% of bladder cancer cases. It is the second most common type of kidney cancer, but accounts for only five to 10 percent of all primary renal malignant tumors. Transitional cell carcinomas arise from the transitional epithelium, a tissue lining the inner surface of these hollow organs.

Related publications (1)

Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results

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