Publication

Covalently immobilized phospholipid bilayers on solid surfaces

Horst Arthur Vogel
1996
Patents

Abstract

A solid coated device is disclosed that has covalently attached a coating which comprises a first layer contg. first functional groups, to which first layer functional groups is covalently attached a second, linking layer carrying second functional groups, to which second, linking layer is covalently attached a third, proximal phospholipid layer, to which third, proximal phospholipid layer is noncovalently attached a fourth, distal lipid layer, so that the proximal and the distal lipid layers together form a bilayer, into which lipid bilayer are optionally inserted receptor mols. A method for prepn. of the bilayers and uses thereof as biosensors or implantation devices also are disclosed. [on SciFinder (R)]

Official source

https://infoscience.epfl.ch/entities/publication/5de65954-2a12-4b6b-8c7e-4f080370adde

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Horst Arthur Vogel
1996
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/5de65954-2a12-4b6b-8c7e-4f080370adde

About this result

Related concepts (32)

Lipid bilayer

The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules. These membranes are flat sheets that form a continuous barrier around all cells. The cell membranes of almost all organisms and many viruses are made of a lipid bilayer, as are the nuclear membrane surrounding the cell nucleus, and membranes of the membrane-bound organelles in the cell. The lipid bilayer is the barrier that keeps ions, proteins and other molecules where they are needed and prevents them from diffusing into areas where they should not be.

Link layer

In computer networking, the link layer is the lowest layer in the Internet protocol suite, the networking architecture of the Internet. The link layer is the group of methods and communications protocols confined to the link that a host is physically connected to. The link is the physical and logical network component used to interconnect hosts or nodes in the network and a link protocol is a suite of methods and standards that operate only between adjacent network nodes of a network segment.

Data link layer

The data link layer, or layer 2, is the second layer of the seven-layer OSI model of computer networking. This layer is the protocol layer that transfers data between nodes on a network segment across the physical layer. The data link layer provides the functional and procedural means to transfer data between network entities and may also provide the means to detect and possibly correct errors that can occur in the physical layer. The data link layer is concerned with local delivery of frames between nodes on the same level of the network.

Related publications (5)

Covalently immobilized phospholipid bilayers on solid surfaces

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