Microstructure informed tractography: pitfalls and open challenges

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Functionally relevant large scale brain dynamics operates within the framework imposed by anatomical connectivity and time delays due to finite transmission speeds. To gain insight on the reliability and comparability of large scale brain network simulatio ...

Background Since the emergence of diffusion tensor imaging, a lot of work has been done to better understand the properties of diffusion MRI tractography. However, the validation of the reconstructed fiber connections remains problematic in many respects. ...

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One of the major limitations of diffusion MRI tractography is that the tractograms, i.e. set of fiber tracts, recovered by existing algorithms are not truly quantitative. Hence, the structural connectivity between different brain regions, a.k.a. connectomi ...

Over the last decades new technologies have shed the light on an improved understanding of brain structure and function. Recently, an imaging modality referred to as diffusion Magnetic Resonance Imaging (dMRI) has emerged. By exploiting the natural motion ...

Microstructure informed tractography: pitfalls and open challenges

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