Publications related to Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow

Related publications (8)

Bacterial-induced Duox-ROS regulates the Imd immune pathway in the gut by modulating the peritrophic matrix

The Duox-reactive oxygen species (ROS) system and the immune deficiency (Imd) pathway play a major role in insect gut immunity. However, their interaction to accomplish an effective immune response is still unclear. Here, we show that Duox regulates the pe ...

2025

Undifferentiated Human Amniotic Fluid Progenitor Cells Promote Bone Regeneration in Vivo

Queralt Vallmajó Martín, Stéphanie Elisabeth Metzger, Anna-Sofia Johanna Kiveliö

The treatment of large bone defects requires bone tissue substitutes. However, the lack of accessible autologous bone, especially in newborns with spina bifida or cleft palate conditions, severely limits therapeutic options involving bone grafts. Here, an ...

WILEY2025

Tracking single hiPSC-derived cardiomyocyte contractile function using CONTRAX an efficient pipeline for traction force measurement

Gaspard Pardon

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) are powerful in vitro models to study the mechanisms underlying cardiomyopathies and cardiotoxicity. Quantification of the contractile function in single hiPSC-CMs at high-through ...

Nature Research2024

An engineered multicellular stem cell niche for the 3D derivation of human myogenic progenitors from iPSCs

Matthias Lütolf, Omid Mashinchian, Jérome Feige

Fate decisions in the embryo are controlled by a plethora of microenvironmental interactions in a three-dimensional niche. To investigate whether aspects of this microenvironmental complexity can be engineered to direct myogenic human-induced pluripotent s ...

WILEY2022

Infection with a small intestinal helminth, Heligmosomoides polygyrus bakeri, consistently alters microbial communities throughout the murine small and large intestine

Nicola Harris, Alexis Rapin, Mario Michael Zaiss, Audrey Geneviève Chuat, Luc Xavier Marie Lebon

Increasing evidence suggests that intestinal helminth infection can alter intestinal microbial communities with important impacts on the mammalian host. However, all of the studies to date utilize different techniques to study the microbiome and access dif ...

2020

Overview of Micro- and Nano-Technology Tools for Stem Cell Applications: Micropatterned and Microelectronic Devices

Carlotta Guiducci

In the past few decades the scientific community has been recognizing the paramount role of the cell microenvironment in determining cell behavior. In parallel, the study of human stem cells for their potential therapeutic applications has been progressing ...

Mdpi Ag2012

Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord

Michele De Palma, Daniela Biziato

Transplanted neural stem/precursor cells possess peculiar therapeutic plasticity and can simultaneously instruct several therapeutic mechanisms in addition to cell replacement. Here, we interrogated the therapeutic plasticity of neural stem/precursor cells ...

2012

Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

Angela Casini

The thioredoxin system plays a key role in regulating the overall intracellular redox balance. It basically comprises the small redox protein thioredoxin (Trx), nicotinamide adenine dinucleotide phosphate, in its reduced form (NADPH), and thioredoxin reduc ...

2009