Publications related to Depth-dependent mechanical properties of human articular cartilage obtained by indentation measurements

Enhancing Chondrocyte Biosynthetic Activities: Harnessing the Power of Loading-Induced Evolved Temperature

Chondrocytes within articular cartilage possess the capacity to perceive and react to signals generated by the typical load-bearing actions of daily life, such as walking or running. Articular cartilage is predominantly oriented toward compression-based fu ...

EPFL2024

Surgical approaches to the capitellum: a comparative anatomic study

Alexandre Terrier, Frédéric Vauclair, Patrick Goetti

Background: Osteochondritis dissecans (OCD) of the humeral capitellum is an important cause of elbow disability in young athletes. Large and unstable lesions sometimes require joint reconstruction with osteochondral autograft. Several approaches have been ...

Mosby-Elsevier2024

Synergetic Support of Cartilage Homeostasis via Coupled Thermal-Hydrostatic Pressure Stimuli

Yanheng Guo

Cartilage homeostasis, crucial for musculoskeletal function, is orchestrated by interconnected biophysical cues. In healthy cartilage, repetitive compressive loading not only elicits a range of mechanical stimuli but also induces a gradual transient temper ...

EPFL2024

Dataset for "Complexity of crack front geometry enhances toughness of brittle solids"

John Martin Kolinski, Chenzhuo Li, Xinyue Wei

This data package supports the publication 'Complexity of crack front geometry enhances toughness of brittle solids' by Xinyue Wei, Chenzhuo Li, Cían McCarthy, and John M. Kolinski Nature physics (2024) - https://doi.org/10.1038/s41567-024-02435-x DOI: 1 ...

Zenodo2024

Multigraded algebras and multigraded linear series

Fatemeh Mohammadi, Yairon Cid Ruiz, Leonid Monin

This paper is devoted to the study of multigraded algebras and multigraded linear series. For an Ns

\mathbb {N}s

-graded algebra A

A

, we define and study its volume function FA:N+s -> R

F_A:\mathbb {N}_+s\rightarrow \mathbb {R}

, which computes the ...

Wiley2024

Can lateral tenodesis improve the rotational stability of the ACL reconstruction? A finite element analysis

Dimitar Yuriev Stanev

One of the most common knee injuries is the Anterior Cruciate Ligament (ACL) rupture with severe implications on knee stability. The usual treatment is the ACL Reconstruction (ACLR) surgery where the surgeon replaces the torn ligament with a graft in an ef ...

Public Library Science2024

Nanoindentation of embedded particles

Andreas Mortensen, Alejandra Inés Slagter, Joris Pierre Everaerts

We address the effect of elastic inhomogeneity on elastic modulus and hardness determinations made by depth-sensing indentations performed on individual particles embedded within a matrix of different elastic modulus. Finite element simulations and nanoind ...

SPRINGER HEIDELBERG2023

Mimicking Loading-Induced Cartilage Self-Heating in Vitro Promotes Matrix Formation in Chondrocyte-Laden Constructs with Different Mechanical Properties

Dominique Pioletti, Naser Nasrollahzadeh Mamaghani, Peyman Karami, Theofanis Stampoultzis, Yanheng Guo

Articular cartilage presents a mechanically sensitive tissue. Chondrocytes, the sole cell type residing in the tissue, perceive and react to physical cues as signals that significantly modulate their behavior. Hyaline cartilage is a connective tissue with ...

2023

FIB-Fabrication of Resonating Cantilevers to Explore Symmetry-Breaking in Quantum Materials

Amelia Emily-Kay Estry

Scientific progress and technological advancements on novel materials are often deterred by limitations on size and quality of samples. Materials with electronic phenomena attractive for applications, and presenting many open scientific questions, are ofte ...

EPFL2023

A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions

Dominique Pioletti, Peyman Karami, Theofanis Stampoultzis, Yanheng Guo

The drive to develop cartilage implants for the treatment of major defects in the musculoskeletal sys-tem has resulted in a major research thrust towards developing biomaterial devices for cartilage repair. Investigational devices for the restoration of ar ...

ELSEVIER SCI LTD2023

Morphological assessment of cartilage and osteoarthritis in clinical practice and research: Intermediate-weighted fat-suppressed sequences and beyond

Tom Hilbert

Magnetic resonance imaging (MRI) is widely regarded as the primary modality for the morphological assessment of cartilage and all other joint tissues involved in osteoarthritis. 2D fast spin echo fat-suppressed intermediate-weighted (FSE FS IW) sequences w ...

SPRINGER2023

Solids that are also liquids: elastic tensors of superionic materials

Nicola Marzari, Giuliana Materzanini, Tommaso Chiarotti

Superionics are fascinating materials displaying both solid- and liquid-like characteristics: as solids, they respond elastically to shear stress; as liquids, they display fast-ion diffusion at normal conditions. In addition to such scientific interest, su ...

NATURE PORTFOLIO2023

GLOBALLY plus -REGULAR VARIETIES AND THE MINIMAL MODEL PROGRAM FOR THREEFOLDS IN MIXED CHARACTERISTIC

Zsolt Patakfalvi, Joseph Allen Waldron

We establish the Minimal Model Program for arithmetic threefolds whose residue characteristics are greater than five. In doing this, we generalize the theory of global F-regularity to mixed characteristic and identify certain stable sections of adjoint lin ...

SPRINGER HEIDELBERG2023

On-Demand Cross-Linkable Bottlebrush Polymers for Voltage- Driven Artificial Muscles

Frank Nüesch, Francis Owusu, Yeerlan Adeli

Dielectric elastomer actuators (DEAs) generate motion resembling natural muscles in reliability, adaptability, elongation, and frequency of operation. They are highly attractive in implantable soft robots or artificial organs. However, many applications of ...

AMER CHEMICAL SOC2023

Shear strength and shear stiffness analysis of compacted Wyoming-type bentonite

Alessio Ferrari

Wyoming-type bentonite is one of the materials to be used as part of the Engineered Barrier System (EBS) in deep geological disposal facilities for the safe disposal of spent nuclear fuel.In the KBS-3 type repository, the canisters containing the spent fue ...

ELSEVIER2023

Bottlebrush Dielectric Elastomers with Improved Properties for Actuation

Yeerlan Adeli

Dielectric elastomer actuators (DEA) are elastic capacitors composed of a pair of compliant electrodes and a soft dielectric elastomer film sandwiched in between. This kind of stretchable capacitors can be actuated when charged, can generate electricity fr ...

EPFL2023

Correlation between sonic pulse velocity and flat-jack tests for the estimation of the elastic properties of unreinforced brick masonry: Case studies from Croatia

Savvas Saloustros

Historic urban cores in southern Europe are characterized by a significant number of existing unreinforced masonry structures that are known for their seismic vulnerability. The first step in the preservation of such damaged buildings is condition assessme ...

2023

On the accuracy of the Conventional gait Model: Distinction between marker misplacement and soft tissue artefact errors

Kamiar Aminian, Arnaud Barré

There is a lack of knowledge about the accuracy of the Conventional Gait Model (CGM), compared to the true bone motion. Accuracy is hindered by both marker misplacement and soft-tissue artefact (STA). The effect of the lateral knee marker (KNE) misplacemen ...

ELSEVIER SCI LTD2023

Diverse parameters of ambulatory knee moments differ with medial knee osteoarthritis severity and are combinable into a severity index

Julien Favre, Brigitte Jolles-Haeberli

Objective: To characterize ambulatory knee moments with respect to medial knee osteoarthritis (OA) severity comprehensively and to assess the possibility of developing a severity index combining knee moment parameters. ...

FRONTIERS MEDIA SA2023

Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation

Dominique Pioletti, François Gorostidi, Theofanis Stampoultzis, Yanheng Guo, Ece Uslu, Vijay Kumar Rana

Tissue wounds are a significant challenge for the healthcare system, affecting millions globally. Current methods like suturing and stapling have limitations as they inadequately cover the wound, fail to prevent fluid leakage, and increase the risk of infe ...

Amer Chemical Soc2023