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The development of fast and mobile drug detection is an important aspect of personalized medicine. It enables the quick assessment of inter-individual differences in drug metabolism and corresponding adjustments of the dose. Recent developments of amperometric biosensors using cytochrome P450 (CYP) show great promise, by lowering the detection limit to physiological range for several drugs via the usage of Multi Walled Carbon Nanotubes (MWCNT). The next challenge is to develop algorithms for processing the resulting sensor data compatible with low-power hardware, which would allow the development of portable battery-powered devices. In this work we pursue a novel approach to this problem. Here we provide a proof of principle by demonstrating how sensor data could be analyzed using a conventional multi-layer perceptron network with error-backpropagation.
Daniel Kuhn, Yves Rychener, Yifan Hu