Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

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Motivation is a multifaceted phenomenon that we explore within the framework of decision-making. Through this cognitive process, actions are directed towards specific goals by performing a trade-off between the cost and benefit of an action. The dorsomedia ...

Electrical stimulation of the visual nervous system could improve the quality of life of patients affected by acquired blindness by restoring some visual sensations, but requires careful optimization of stimulation parameters to produce useful perceptions. ...

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The temporal variability of the thalamus in functional networks may provide valuable insights into the pathophysiology of schizophrenia. To address the complexity of the role of the thalamic nuclei in psychosis, we introduced micro-co-activation patterns ( ...

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While humans are known to have several premotor cortical areas, secondary motor cortex (M2) is often considered to be the only higher -order motor area of the mouse brain and is thought to combine properties of various human premotor cortices. Here, we sho ...

Cell fate progression of pluripotent progenitors is strictly regulated, resulting in high human cell diversity. Epigenetic modifications also orchestrate cell fate restriction. Unveiling the epigenetic mechanisms underlying human cell diversity has been di ...

IntroductionThe current assessment and standardization of microsurgical skills are subjective, posing challenges in reliable skill evaluation. We aim to address these limitations by developing a quantitative and objective framework for accurately assessing ...

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

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Neurobiological and metabolic basis of motivation and effort-based decision-making - A human 1H-MRS, fMRI and machine learning study

Decoding electroencephalographic responses to visual stimuli compatible with electrical stimulation

Small-scale robotic devices for medical interventions in the brain

Thalamic contributions to psychosis susceptibility: Evidence from co-activation patterns accounting for intra-seed spatial variability (μCAPs)

Involvement of prelimbic cortex neurons and related circuits in the acquisition of a cooperative learning by pairs of rats

Fast adaptation to rule switching using neuronal surprise

Modeling, fabrication and validation of 3D neural interfaces for peripheral nerves and brain organoids

The interplay between white adipose tissue, adipokines, and structural gray matter changes

The mouse motor system contains multiple premotor areas and partially follows human

Single-cell epigenomic reconstruction of developmental trajectories from pluripotency in human neural organoid systems

An objective skill assessment framework for microsurgical anastomosis based on ALI scores