Publication

Modulation of mitophagy and use thereof

Didier Trono, Isabelle Barde
2014
Patents

Abstract

The present invention relates to an agent or composition comprising at least one of: (i) a micro-RNA targeting a mitophagy-associated gene or a variant thereof, (ii) a vector comprising a nucleic acid encoding said micro-RNA or variant thereof, (iii) an inducer of said micro-RNA, and (iv) an inhibitor of said micro-RNA, for use as a medicament. In particular, the invention relates to substances and compositions useful in the treatment of mitochondria-related diseases, in a subject, or to enhance protocols of in vitro production of red blood cells.

Official source

https://infoscience.epfl.ch/entities/publication/565a92c7-80d4-4dd8-ad06-f23cd2ee3b36

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Modulation of mitophagy and use thereof

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