Publication

Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys

Didier Trono, Henning Paul-Julius Stahlberg, Florence Pojer, Priscilla Turelli, Kelvin Ka Ching Lau, Charlène Mireille Raymonde Raclot, Yoan Désiré Duhoo, Myriam Isabelle Lamrayah, Vanessa Genet
2023
Journal Articles

Abstract

Due to the rapid evolution of SARS-CoV-2 to variants with reduced sensitivity to vaccine-induced humoral immunity and the near complete loss of protective efficacy of licensed therapeutic monoclonal antibodies, we isolated a potent, broad-spectrum neutralizing antibody that could potentially provide prophylactic protection to immunocompromised patient populations.

Official source

https://infoscience.epfl.ch/entities/publication/4f14fae6-347e-47fe-b3e9-a3341d2fd7c9

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Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys

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