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The invention relates to an additive which can be added to buffers used in nucleotide detection processes and improved methods of nucleic acid sequencing using this additive. In particular the invention relates to use of the additive to improve the efficiency of fluorescence-based multiple cycle nucleic acid sequencing reactions
Ardemis Anoush Boghossian, Yahya Rabbani, Shang-Jung Wu, Vitalijs Zubkovs, Sayyed Hashem Sajjadi
Volkan Cevher, Efstratios Panteleimon Skoulakis, Leello Tadesse Dadi, Ioannis Mavrothalassitis