Publication

(Quantum) Fisher Information in Localization Microscopy

2025

Abstract

The precise localization of particles yields structural and dynamical information in applications ranging from fundamental physics to molecular biology. Here, we discuss how the concept of (Quantum) Fisher information can guide the development of localization techniques. Starting from dipole scattering, we discuss imaging based on elastic and inelastic (e.g. fluorescence) scattering and present experimental designs that increase the information obtained per detected photon.

Official source

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

2025

Abstract

Official source

Related concepts (32)

Raman scattering

Raman scattering or the Raman effect (ˈrɑːmən) is the inelastic scattering of photons by matter, meaning that there is both an exchange of energy and a change in the light's direction. Typically this effect involves vibrational energy being gained by a molecule as incident photons from a visible laser are shifted to lower energy. This is called normal Stokes Raman scattering. The effect is exploited by chemists and physicists to gain information about materials for a variety of purposes by performing various forms of Raman spectroscopy.

Rayleigh scattering

Rayleigh scattering (ˈreɪli ), named after the 19th-century British physicist Lord Rayleigh (John William Strutt), is the predominantly elastic scattering of light or other electromagnetic radiation by particles much smaller than the wavelength of the radiation. For light frequencies well below the resonance frequency of the scattering particle (normal dispersion regime), the amount of scattering is inversely proportional to the fourth power of the wavelength. Rayleigh scattering results from the electric polarizability of the particles.

Scattering

Scattering is a term used in physics to describe a wide range of physical processes where moving particles or radiation of some form, such as light or sound, are forced to deviate from a straight trajectory by localized non-uniformities (including particles and radiation) in the medium through which they pass. In conventional use, this also includes deviation of reflected radiation from the angle predicted by the law of reflection.

Related publications (32)

(Quantum) Fisher Information in Localization Microscopy

Chat with Graph Search

Refined Spin Hamiltonian on the Cairo Pentagonal Lattice of Bi2fe4o9

Power and limitations of learning quantum dynamics incoherently

Refolding-assisted purification of native full-length TDP-43 compatible with BSL-2 safety regulations