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Through site-specific generation of intermediary reactive aldehydes, Horner-Wadsworth-Emmons olefination can now deliver selective functionalization of stable recombinant proteins and monoclonal antibodies, whilst preserving protein integrity.
Katrin Beyer, Frédéric Kaplan, Bryan German Pantoja Rosero, Alexander Michael Rusnak
Paul Joseph Dyson, Xinbang Wu, Mingyang Liu