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The effect of Fe2+, Fe3+, H2O2 and the photo-Fenton system (Fe2+or3+/H2O2/hv) on solar water disinfection (SODIS) at low temperature and at near neutral pH are discussed in detail. We focus on Escherichia coil K12 suspended in either MilliQ water, water containing mineral ions and in MilliQ water enriched with resorcinol, a model for natural organic matter (NOM).