Publication

Model Organisms Proteomics-From Holobionts to Human Nutrition

2013
Journal Articles

Abstract

Model organisms are an important tool for the development and validation of analytical approaches for proteomics and for the study of basic mechanisms of biological processes. The Initiative on Model Organism Proteomics (iMOP) organized a session during the 11th HUPO world congress in Boston in 2012, highlighting the potential of proteomics studies in model organism for the elucidation of important mechanisms regulating the interaction of humans with its environment. Major subjects were the use of model organisms for the study of molecular events triggering the interaction of host organisms with the surrounding microbiota and the elucidation of the complex influence of nutrition on the health of human beings.

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https://infoscience.epfl.ch/entities/publication/48d1f64b-3f0c-4da8-9c22-b30df81e63fc

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2013
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/48d1f64b-3f0c-4da8-9c22-b30df81e63fc

About this result

Related concepts (27)

Model organism

A model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical. This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution.

Proteomics

Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system.

Genetically modified organism

A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with the most common being an organism altered in a way that "does not occur naturally by mating and/or natural recombination". A wide variety of organisms have been genetically modified (GM), from animals to plants and microorganisms.

Related publications (29)

Model Organisms Proteomics-From Holobionts to Human Nutrition

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Reconstruction and analysis of genome-scale metabolic networks in single organisms and microbial communities

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Industrial Biotechnology Conservation Processes: Similarities with Natural Long-Term Preservation of Biological Organisms