Polymers at the Interface with Biology

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The stiffness of cells and of their nuclei is a biomarker of several pathological conditions. Current measurement methods rely on invasive physical probes that yield one or two stiffness values for the whole cell. However, the internal distribution of cell ...

Whole-cell biophotovoltaic (BPV) devices leverage photoautotrophic microorganisms like cyanobacteria to convert sunlight and water into bioelectricity. They are capable of growing on sequestered carbon dioxide (CO2), eliminating the need to add exogenous o ...

Chlorinated compounds are ubiquitous. However, accumulation of chlorine-containing waste has a negative impact on human health and the environment due to the inapplicability of common disposal methods, such as landfill and incineration. Here we report a su ...

Solid-state electrolytes, particularly polymer/ceramic composite electrolytes, are emerging as promising candidates for lithium-ion batteries due to their high ionic conductivity and mechanical flexibility. The interfaces that arise between the inorganic a ...

The term 'brain-computer interface' (BCI) is widely used. However, even among experts, its meaning can sometimes be unclear 1-3. Lack of clarity from the term has real-world implications: it can muddle regulatory guidelines, it may confuse investors, it ca ...

The limitations of 2D microscopy constrain our ability to observe and understand tissue-wide networks that are, by nature, 3-dimensional. Optical projection tomography (OPT) enables the acquisition of large volumes (ranging from micrometres to centimetres) ...

Single-cell sequencing (sc-seq) provides a species agnostic tool to study cellular processes. However, these technologies are expensive and require sufficient cell quantities and biological replicates to avoid artifactual results. An option to address thes ...

Recent advancements in miniature devices with higher computational capabilities and ultralow power consumption have accelerated the development of wearable sensors, actuators, and energy harvesters everywhere. The ultimate aim of such a technological revol ...

Thermoset rubbers give rise to elastomers with tunable stiffness and high resilience but are not recyclable. Thermoplastic elastomers can address this problem but their broad applicability is impeded by either limited operating temperatures or inferior ela ...

Imaging technologies drive discovery in cell biology. Innovations in microscopy hardware, imaging methods and computational analysis of large-scale, complex datasets can increase imaging resolution, definition and allow access to new biology. We asked expe ...

In the era of "big data" finding solutions for data storage alternative to those based on silicon or magnetic tapes is an urgent need for our society. The development of polymers that can store information at the molecular level has opened up new opportuni ...

Infections caused by multidrug-resistant (MDR) bacteria pose an impending threat to humanity, as the evolution of MDR bacteria outpaces the development of effective antibiotics. In this work, we use indium phosphide (InP) quantum dots (QDs) to treat infect ...

The billion tons of synthetic-polymer-based materials (i.e. plastics) produced yearly are a great challenge for humanity. Nature produces even more natural polymers, yet they are sustainable. Proteins are sequence-defined natural polymers that are constant ...

Circulation of the cerebrospinal fluid (CSF) contributes to body axis formation and brain development. Here, we investigated the unexplained origins of the CSF flow bidirectionality in the central canal of the spinal cord of 30 hpf zebrafish embryos and it ...

Previously, we showed that cryo fixation of adult mouse brain tissue gave a truer representation of brain ultrastructure in comparison with a standard chemical fixation method (Korogod et al., 2015). Extracellular space matched physiological measurements, ...

Changes to the structure and function of neural networks are thought to underlie the evolutionary adaptation of animal behaviours. Among the many developmental phenomena that generate change programmed cell death (PCD) appears to play a key role. We show t ...

Room temperature ionic liquids are salts which are molten at or around room temperature without any added solvent or solution. In bulk they exhibit glass like dependence of conductivity with temperature as well as coupling of structural and transport prope ...

We consider nonparametric estimation of a covariance function on the unit square, given a sample of discretely observed fragments of functional data. When each sample path is observed only on a subinterval of length , one has no statistical information on ...

A new conducting polymer poly (3, 4-phenylenedioxythiophene) is synthesized by the electrochemical polymerization technique with different solvents. We find that solvents used in electrochemical polymerization play important roles for the catalytic activit ...

One of the great challenges in biology is to understand the mechanisms by which morphogenetic processes arise from molecular activities. We investigated this problem in the context of actomyosin-based cortical flow in C. elegans zygotes, where large-scale ...

Polymers at the Interface with Biology

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Estimation of Stiffness Maps in Deforming Cells Through Optical Flow With Bounded Curvature

Bioanode engineering for living solar cells

Tandem catalysis enables chlorine-containing waste as chlorination reagents

Ion Transport at Polymer-Argyrodite Interfaces

An application-based taxonomy for brain–computer interfaces

Optical imaging of the small intestine immune compartment across scales

Evaluation of genetic demultiplexing of single-cell sequencing data from model species

Tailor-made Piezoelectric Elastomer Materials

Reinforced Supramolecular Networks of End Functionalized Polymers for Tailored Thermomechanical Property Profiles

Imaging cell biology

Bacterial nanopores open the future of data storage

Photodynamic treatment of multidrug-resistant bacterial infection using indium phosphide quantum dots

Nature-Inspired Circular-Economy Recycling for Proteins: Proof of Concept

Origin and role of the cerebrospinal fluid bidirectional flow in the central canal

Ultrastructural comparison of dendritic spine morphology preserved with cryo and chemical fixation

Extensive and diverse patterns of cell death sculpt neural networks in insects

Nanocapillary confinement of imidazolium based ionic liquids

Recovering covariance from functional fragments

Electrochemically polymerized poly (3, 4-phenylenedioxythiophene) as efficient and transparent counter electrode for dye sensitized solar cells

Morphogenetic degeneracies in the actomyosin cortex