Validation of a patient-specific one-dimensional model of the systemic arterial tree

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This work deals with tailored reduced order models for bifurcating nonlinear parametric partial differential equations, where multiple coexisting solutions arise for a given parametric instance. Approaches based on proper orthogonal decomposition have been ...

Background:Arterial stiffening contributes to hemodynamic derangements in heart failure with preserved ejection fraction (HFpEF). We sought to investigate the impact of renal denervation on pulsatile left ventricular loading in patients with HFpEF and hype ...

Aortic diseases are characterized by dire prognosis and inadequate diagnosis, owing to their insidious yet lethal nature. Aortopathies, namely aortic aneurysms and dissections, along with certain congenital diseases, might necessitate surgical replacement ...

Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram (PPG) signals contain a wealth of information on the cardiovascular (CV) system that can be exploited to assess vascular age and identify individuals at elevated CV risk. We review th ...

Aortic diastolic pressure decay (DPD) has been shown to have considerable pathophysiological relevance in the assessment of vascular health, as it is significantly affected by arterial stiffening. Nonetheless, the aortic pressure waveform is rarely availab ...

The transaortic valvular pressure gradient (TPG) plays a central role in decision-making for patients suffering from severe aortic stenosis. However, the flow-dependence nature of the TPG makes the diagnosis of aortic stenosis challenging since the markers ...

Dielectric elastomer actuator augmented aorta (DEA) represents a novel approach with high potential for assisting a failing heart. The soft tubular device replaces a section of the aorta and increases its diameter when activated. The hemodynamic interactio ...

Fast camera imaging is used to study ion acoustic waves propagating azimuthally in a magnetized plasma column. The high-speed image sequences are analyzed using proper orthogonal decomposition and 2D Fourier transform, allowing to evaluate the assets and d ...

Blood pressure (BP) is a crucial indicator of cardiovascular health. Hypertension is a common life-threatening condition and a key factor of cardiovascular diseases (CVDs). Identifying abnormal BP fluctuations can allow for early detection and management o ...

Introduction: Synthetic vascular grafts have been widely used in clinical practice for aortic replacement surgery. Despite their high rates of surgical success, they remain significantly less compliant than the native aorta, resulting in a phenomenon calle ...

Background: Cardiac output is essential for patient management in critically ill patients. The state-of-the-art for cardiac output monitoring bears limitations that pertain to the invasive nature of the method, high costs, and associated complications. Hen ...

We introduce a reconfigurable medium for the manipulation of elastic propagation properties of Lamb waves. It is based on a shape memory polymer (SMP) with temperature-dependent Young's modulus. Waves are excited by a laser pulse and detected by a laser vi ...

The integration of technology in the medical field has greatly improved accuracy in diagnoses, thus leading to more effective treatments. Wearable and implantable medical devices offer great potential for remote patient monitoring, particularly for heart f ...

Hypertension is the most common cause of left ventricular hypertrophy, contributing to heart failure progression. Candesartan (Cand) is an angiotensin receptor antagonist widely used for hypertension treatment. Structural modifications were previously perf ...

Photoplethysmography (PPG) is a widely emerging method to assess vascular health in humans. The origins of the signal of reflective PPG on peripheral arteries have not been thoroughly investigated. We aimed to identify and quantify the optical and biomecha ...

Self-healing slip pulses are major spatiotemporal failure modes of frictional systems, featuring a characteristic size L(t) and a propagation velocity c(p)(t) (t is time). Here, we develop a theory of slip pulses in realistic rate- and state-dependent fric ...

In this thesis, we unveil a third design path to manipulate elastic waves within architected media, distinct from the traditional phononic crystal and locally-resonant metamaterial concepts. The core innovation lies in the concept of nonlocal resonances, d ...

Reducing the computational time required by high-fidelity, full-order models (FOMs) for the solution of problems in cardiac mechanics is crucial to allow the translation of patient-specific simulations into clinical practice. Indeed, while FOMs, such as th ...

Correct prediction of particle transport by surface waves is crucial in many practical applications such as search and rescue or salvage operations and pollution tracking and clean-up efforts. Recent results by Deike et al. (J. Fluid Mech., vol. 829, 2017, ...

Acoustic emission (AE) monitoring is commonly used to inspect the health of a structure continuously. During fracture processes elastic waves of AE are created and emitted, and sensors can capture these waves. The acquired signals can be processed to track ...

Validation of a patient-specific one-dimensional model of the systemic arterial tree

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Deflation-based certified greedy algorithm and adaptivity for bifurcating nonlinear PDEs

Modulation of Pulsatile Left Ventricular Afterload by Renal Denervation in Heart Failure With Preserved Ejection Fraction

Compliance-matching vascular grafts with personalization potential

Arterial pulse wave modeling and analysis for vascular-age studies: a review from VascAgeNet

On the similarity between aortic and carotid pressure diastolic decay: a mathematical modelling study

The Impact of Left Ventricular Performance and Afterload on the Evaluation of Aortic Valve Stenosis: A 1D Mathematical Modeling Approach

Hemodynamic effects of a dielectric elastomer augmented aorta on aortic wave intensity: An in-vivo study

Nonlinear interactions of ion acoustic waves explored using fast imaging decompositions

Data-driven approaches for non-invasive cuffless blood pressure monitoring

Design and computational optimization of compliance-matching aortic grafts

Cardiac output estimated from an uncalibrated radial blood pressure waveform: validation in an in-silico-generated population

Optimization of elastic wave propagation in a reconfigurable medium by genetic algorithms with adaptive mutation probability

Integrated Electronics for Deep Implants to Remotely Monitor Hemodynamics

Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy

Quantification of the Phenomena Affecting Reflective Arterial Photoplethysmography

The dynamics of unsteady frictional slip pulses

Nonlocally-resonant metamaterials

Efficient approximation of cardiac mechanics through reduced-order modeling with deep learning-based operator approximation

Stochastic particle transport by deep-water irregular breaking waves

Automatic and high-precision microseismic monitoring of progressive failure prior, during, and after tunnel excavation