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The C–H functionalization of inert alkanes has long been one of the most challenging reactions in organic synthesis. Now, the use of hypervalent iodine reagents has enabled the diverse functionalization of various aliphatic C–H bonds under blue light irradiation, achieving a high level of reactivity and selectivity.
Jeremy Luterbacher, Songlan Sun, Lorenz Perry Manker, Shasha Zheng
Philippe Schwaller, Junwu Chen